| Autor: |
Toriyama K; Department of Gastroenterology, Aichi Cancer Center Hospital., Hijioka S; Department of Gastroenterology, Aichi Cancer Center Hospital.; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital., Oseto K; Department of Breast Oncology, Aichi Cancer Center Hospital., Mizuno N; Department of Gastroenterology, Aichi Cancer Center Hospital., Tanaka T; Department of Endoscopy, Aichi Cancer Center Hospital., Ishihara M; Department of Endoscopy, Aichi Cancer Center Hospital., Tajika M; Department of Endoscopy, Aichi Cancer Center Hospital., Shimizu Y; Department of Gastroenterological Surgery, Aichi Cancer Center Hospital., Hara K; Department of Gastroenterology, Aichi Cancer Center Hospital., Niwa Y; Department of Endoscopy, Aichi Cancer Center Hospital. |
| Abstrakt: |
Two cases of multiple endocrine neoplasia type 1 are reported. In both cases, computed tomography (CT) showed hypervascular lesions of the pancreas. Endoscopic ultrasound showed multiple lesions in the pancreas, and each case was diagnosed as pancreatic neuroendocrine tumor by EUS-FNA. In addition to a pancreatic neuroendocrine tumor, case 1 had hyperparathyroidism and case 2 had a history of parathyroid tumor. Furthermore, case 1 had a family history of pancreatic tumor and case 2 had a family history of pancreatic tumor and parathyroid resection. From these indications, multiple endocrine neoplasia type 1 was diagnosed by genetic testing. As demonstrated in these two cases, it is important to consider multiple endocrine neoplasia type 1 when diagnosing pancreatic neuroendocrine tumor. |
