Alcohol use disorder relapse factors: A systematic review.

Autor: Sliedrecht W; De Hoop GGZ, Provincialeweg 70, 3329 KP Dordrecht, the Netherlands. Electronic address: w.sliedrecht@dehoop.org., de Waart R; Mentrum/Arkin, Wisselwerking 46-48, 1112 XR Diemen, the Netherlands. Electronic address: ranne.de.waart@mentrum.nl., Witkiewitz K; The University of New Mexico (UNM), MSC 03-2220, Univ of New Mexico, Albuquerque, NM 87131, USA. Electronic address: katiew@unm.edu., Roozen HG; The University of New Mexico (UNM), Center on Alcoholism, Substance Abuse, and Addictions (CASAA), MSC 11 6280, 1 Univ of New Mexico, Albuquerque, NM 87106, USA. Electronic address: hroozen@unm.edu.
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 2019 Aug; Vol. 278, pp. 97-115. Date of Electronic Publication: 2019 May 25.
DOI: 10.1016/j.psychres.2019.05.038
Abstrakt: A relapsing-remitting course is very common in patients with an Alcohol Use Disorder (AUD). Understanding the determinants associated with alcohol resumption remains a formidable task. This paper examines relapse determinants based on a systematic review of recent alcohol literature (2000-2019). Relevant databases were consulted for articles that contained information about specific relapse determinants and reported statistical significance of each relapse determinant in predicting relapse. Relapse was broadly defined based on the characterization in the included articles. From the initial identified 4613 papers, a total of 321 articles were included. Results encompass multiple relapse determinants, which were ordered according to biopsychosocial and spiritual categories, and presented, using a descriptive methodology. Psychiatric co-morbidity, AUD severity, craving, use of other substances, health and social factors were consistently significantly associated with AUD relapse. Conversely, supportive social network factors, self efficacy, and factors related to purpose and meaning in life, were protective against AUD relapse. Despite heterogeneity in different methods, measures, and sample characteristics, these findings may contribute to a better therapeutic understanding in which specific factors are associated with relapse and those that prevent relapse. Such factors may have a role in a personalized medicine framework to improve patient outcomes.
(Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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