Luminescent Ru(ii)-thiol modified silver nanoparticles for lysosome targeted theranostics.

Autor: Wumaier M; Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200092, PR China. shishuo@tongji.edu.cn tmyao@tongji.edu.cn., Yao TM; Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200092, PR China. shishuo@tongji.edu.cn tmyao@tongji.edu.cn., Hu XC; Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200092, PR China. shishuo@tongji.edu.cn tmyao@tongji.edu.cn., Hu ZA; Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200092, PR China. shishuo@tongji.edu.cn tmyao@tongji.edu.cn., Shi S; Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200092, PR China. shishuo@tongji.edu.cn tmyao@tongji.edu.cn and Biomedical Multidisciplinary Innovation Research Institute, Shanghai East Hospital, Tongji University, Shanghai 200092, PR China.
Jazyk: angličtina
Zdroj: Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2019 Jul 16; Vol. 48 (28), pp. 10393-10397.
DOI: 10.1039/c9dt00878k
Abstrakt: Silver nanoparticles (AgNPs) modified by luminescent Ru(ii) complexes not only possess bright red fluorescence but also can target lysosomes. Cell imaging and a cytotoxicity study suggest that Ru1-2·AgNPs may act as a potential theranostic agent.
Databáze: MEDLINE