Infantile Optic Pathway Glioblastoma.

Autor: Siedler DG; Department of Neurosurgery, Royal Hobart Hospital, Hobart, Tasmania, Australia., Beechey JC; Department of Anatomical Pathology, Royal Hobart Hospital, Hobart, Tasmania, Australia., Jessup PJ; Department of Anatomical Pathology, Royal Hobart Hospital, Hobart, Tasmania, Australia., Thani NB; Department of Neurosurgery, Royal Hobart Hospital, Hobart, Tasmania, Australia. Electronic address: novathani@gmail.com.
Jazyk: angličtina
Zdroj: World neurosurgery [World Neurosurg] 2019 Sep; Vol. 129, pp. 172-175. Date of Electronic Publication: 2019 May 31.
DOI: 10.1016/j.wneu.2019.05.236
Abstrakt: Background: Optic pathway gliomas and glioblastomas remain a rare entity within the infant population.
Case Description: We outline the case of a 6-month-old female who presented with failure to thrive, nystagmus and features of raised intracranial pressure. Subsequent magnetic resonance imaging demonstrated an infiltrating tumor radiating from the optic nerves bilaterally. She underwent emergent ventriculoperitoneal shunting and biopsy. Histology confirmed a World Health Organization grade IV glioblastoma.
Conclusions: The patient remained clinically and radiologically stable at 1 year. Optic pathway glioblastoma in this population is a previously undescribed entity that requires multidisciplinary input to guide ongoing therapy.
(Copyright © 2019 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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