Dural-Based Frontal Lobe Hemangioblastoma.

Autor: Vicente Lacerda RA; Internal Medicine Department, Medical School of Juazeiro do Norte, Juazeiro do Norte, Ceará, Brazil., Teixeira Júnior AG; Internal Medicine Department, Federal University of Cariri, Barbalha, Ceará, Brazil., Sauaia Filho EN; Department of Neurosurgery, General Hospital of Fortaleza, Fortaleza, Ceará, Brazil., de Macêdo Filho LJM; Health Science Center, University of Fortaleza, Fortaleza, Ceará, Brazil. Electronic address: leonardomacedofilho@edu.unifor.br., Antônio AS; Department of Neurosurgery, General Hospital of Fortaleza, Fortaleza, Ceará, Brazil., Cabral JA; Department of Neurosurgery, General Hospital of Fortaleza, Fortaleza, Ceará, Brazil., Ramos Júnior F; Department of Neurosurgery, General Hospital of Fortaleza, Fortaleza, Ceará, Brazil., Valença Júnior JT; Medical School, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Jazyk: angličtina
Zdroj: World neurosurgery [World Neurosurg] 2019 Sep; Vol. 129, pp. 18-23. Date of Electronic Publication: 2019 May 29.
DOI: 10.1016/j.wneu.2019.05.175
Abstrakt: Background: Hemangioblastomas are benign vascular neoplasms that may be associated with von Hippel-Lindau disease. They are more common in men, with a mean age of 36 years, and rarely affect the supratentorial region and, when present in this topography, do not have meningeal impairment. Diagnosis by the radiologic and histopathologic study is difficult, since they are rare and, therefore, forgotten diagnosis, besides they are differential diagnoses with other supratentorial neoplasms.
Case Description: The present report describes a case of a frontal hemangioblastoma in a 64-year-old woman who presented with seizures. Our imaging studies had as a main hypothesis a frontal meningioma because of dural tail sign, lack of edema, contrast enhancement pattern, and extra-axial location in the supratentorial region, in the frontal lobe, which is uncommon for a hemangioblastoma. The patient underwent microneurosurgery for tumor resection, and the excised tissue was submitted for anatomopathologic evaluation. This study clarified the diagnosis as hemangioblastoma. We followed up the patient at the outpatient clinic for 2 years, with clinical improvement, without tumor recurrence. We also compared the clinical, radiologic, epidemiologic, and anatomopathologic data of the reported case with data from a literature review conducted through the PubMed portal.
Conclusions: Definitive treatment for these lesions is surgical resection. Physicians should be aware that supratentorial meningeal hemangioblastomas can be developed in a patient without von Hippel-Lindau disease and regular follow-up is mandatory.
(Copyright © 2019 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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