Community-Based Care in the ANRS-IPERGAY Trial: The Challenges of Combination Prevention.

Autor:	Puppo C; GRePS, Lyon 2 University, Lyon, France., Mabire X; GRePS, Lyon 2 University, Lyon, France., Cotte L; Hôpital Croix Rousse, Lyon, France., Castro DR; Coalition Plus, Paris, France.; Aix Marseille Univ, INSERM, IRD, SESSTIM, Marseille, France., Spire B; Aix Marseille Univ, INSERM, IRD, SESSTIM, Marseille, France.; ORS PACA, Southeastern Health Regional Observatory, Marseille, France., Cua E; Hôpital de l'Archet, Nice, France., Pialoux G; Hôpital Tenon, Paris, France., Monti MS; Aix Marseille Univ, INSERM, IRD, SESSTIM, Marseille, France.; ORS PACA, Southeastern Health Regional Observatory, Marseille, France., Pasquet A; Hôpital de Tourcoing, France., Raffi F; CHU Hôtel Dieu, Nantes, France., Molina JM; Hôpital Saint-Louis, Department of Infectious Disease, Assistance Publique Hôpitaux de Paris, Paris, France., Préau M; GRePS, Lyon 2 University, Lyon, France.
Jazyk:	angličtina
Zdroj:	AIDS education and prevention : official publication of the International Society for AIDS Education [AIDS Educ Prev] 2019 Jun; Vol. 31 (3), pp. 259-272.
DOI:	10.1521/aeap.2019.31.3.259
Abstrakt:	ANRS-IPERGAY was a community-based randomized trial investigating the efficacy of sexual activity-based HIV pre-exposure prophylaxis (PrEP) in a population of males and transgender females who had sex with men and were at high risk of HIV infection. We qualitatively analyzed the support provided to participants by community-based health workers (CBHW) throughout the trial's double-blind and open-label extension phases. In particular, we showed that the relationship between participants and CBHW strongly influenced self-managed pill intake. The delicate construction of this relationship, balanced between trust and dependence, played an important role in PrEP adherence. CBHW had to deal with various issues surrounding participants' feelings of empowerment regarding their role in the trial, as well as related tensions between various logics and rationalities. They were essential to participants' continued involvement.
Databáze:	MEDLINE
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