Diagnostic Accuracy of a MR Protocol Acquired with and without Endorectal Coil for Detection of Prostate Cancer: A Multicenter Study.

Autor: Barth BK; Institute of Diagnostic and Interventional Radiology, Zurich., Rupp NJ; Department of Pathology and Molecular Pathology, Zurich., Cornelius A; Department of Urology, University Hospital Zurich and University of Zurich, Zurich., Nanz D; Institute of Diagnostic and Interventional Radiology, Zurich.; Department of Radiology, Zurich., Grobholz R; Institute for Pathology, Switzerland., Schmidtpeter M; Swiss Center for Musculoskeletal Imaging, Balgrist Campus AG, Zurich.; Department of Urology, Cantonal Hospital Aarau, Aarau., Wild PJ; Department of Pathology and Molecular Pathology, Zurich.; Urologiepraxis Lenzburg, Lenzburg, Switzerland., Eberli D; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany., Donati OF; Institute of Diagnostic and Interventional Radiology, Zurich.
Jazyk: angličtina
Zdroj: Current urology [Curr Urol] 2019 Mar 08; Vol. 12 (2), pp. 88-96.
DOI: 10.1159/000489425
Abstrakt: Introduction: The purpose of this study was to compare diagnostic accuracy of a prostate multiparametric magnetic resonance imaging (mpMRI) protocol for detection of prostate cancer between images acquired with and without en-dorectal coil (ERC).
Materials: This study was approved by the regional ethics committee. Between 2014 and 2015, 33 patients (median age 51.3 years; range 42.1-77.3 years) who underwent prostate-MRI at 3T scanners at 2 different institutions, acquired with (mpMRI ERC ) and without (mpMRI PPA ) ERC and who received radical prostatectomy, were included in this retrospective study. Two expert readers (R1, R2) attributed a PI-RADS version 2 score for the most suspect (i. e. index) lesion for mpMRI PPA and mpMRI ERC . Sensitivity and positive predictive value for detection of index lesions were assessed using 2 × 2 contingency tables. Differences between groups were tested using the McNemar test. Whole-mount histopathology served as reference standard.
Results: On a quadrant-basis cumulative sensitivity ranged between 0.61-0.67 and 0.76-0.88 for mpMRI PPA and mpMRI ERC protocols, respectively (p > 0.05). Cumulative positive predictive value ranged between 0.80-0.81 and 0.89-0.91 for mpMRI PPA and mpMRI ERC protocols, respectively. The differences were not statistically significant for R1 (p = 0.267) or R2 (p = 0.508).
Conclusion: Our results suggest that there may be no significant differences for detection of prostate cancer between images acquired with and without an ERC.
Databáze: MEDLINE
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