In utero embolization for placental chorioangioma and neonatal multifocal hemangiomatosis.

Autor: Hamouda S; Department of Gynaecology and Obstetrics, Gynepole, AP-HM, Assistance Publique-Hôpitaux de Marseille, AMU, Aix-Marseille Université, France., Soussan J; Department of Radiology, North University Hospital, Chemin des Bourrely, 13015 Marseille, France., Haumonté JB; Hopital Saint Joseph, Department of Gynaecology and Obstetrics, Marseille, France., Bretelle F; Department of Gynaecology and Obstetrics, Gynepole, AP-HM, Assistance Publique-Hôpitaux de Marseille, AMU, Aix-Marseille Université, France; Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France. Electronic address: florence.bretelle@ap-hm.fr.
Jazyk: angličtina
Zdroj: Journal of gynecology obstetrics and human reproduction [J Gynecol Obstet Hum Reprod] 2019 Oct; Vol. 48 (8), pp. 689-694. Date of Electronic Publication: 2019 May 18.
DOI: 10.1016/j.jogoh.2019.05.011
Abstrakt: Placental chorioangioma is a limited non trophoblastic vascular tumour that may causes fetal complications as well as post-natal ones. We reported in here the first case of an in utero embolization of chorioangioma diagnosed at 22 W G with a post-natal diagnosis of neonatal multifocal hemangioma with a good outcome. The chorioangioma was embolized using GLUBRAN 2 ® (cyanolacrylate) a biologic surgical glue at 26 W G. Premature rupture of membrane occurred at 28 W G. A cesarean section at 32 W G was performed for retro placental hematoma. The neonate was 1400 g healthy girl with an anemia (hemoglobin 9.7 g/dl). After one month of life, the child met a neonatal multifocal hemangioma (skin and liver were involved) with superficial erosion of skin hemangiomas that required post-natal transfusions. We propose a literature review related to the various technics of in utero treatment of placental chorioangioma and the links with neonatal multifocal hemangiomatosis as well. The girl is now 7 year old and has a normal neurodevelopmental outcome.
(Copyright © 2019. Published by Elsevier Masson SAS.)
Databáze: MEDLINE
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