[Intestinal microbiota: relationship to age-associated diseases (review of literature).]

Autor: Bulgakova SV; Samara State Medical University, 43099, Samara, Russia., Treneva EV; Samara State Medical University, 43099, Samara, Russia., Zakharova NO; Samara State Medical University, 43099, Samara, Russia., Trukhanova IG; Samara State Medical University, 43099, Samara, Russia.
Jazyk: ruština
Zdroj: Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2019; Vol. 64 (4), pp. 250-256.
DOI: 10.18821/0869-2084-2019-64-4-250-256
Abstrakt: In connection with the increase in life expectancy, the number of people of older age groups is increasing, and with it the age of associated diseases, which are of tremendous medical and social importance. Such diseases include Alzheimer's disease, osteoporosis, sarcopenia, atherosclerosis and other cardiovascular pathology. The role of the gut microbiota in the pathogenesis of these nosologies is widely discussed in the literature. In addition, a number of studies have shown the effectiveness of the use of probiotics and prebiotics in the treatment of these diseases. The review of the literature summarizes the current understanding of the role of the intestinal microbiota in the development, prevention, and treatment of major age-related diseases.
Competing Interests: The authors declare no conflict of interest.
Databáze: MEDLINE