French infant total diet study: Dietary exposure to heat-induced compounds (acrylamide, furan and polycyclic aromatic hydrocarbons) and associated health risks.
Autor: | Sirot V; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 Rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France. Electronic address: sirotv@gmail.com., Rivière G; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 Rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Leconte S; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 Rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Vin K; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 Rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Traore T; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 Rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Jean J; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 Rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Carne G; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 Rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Gorecki S; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 Rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Veyrand B; LABERCA, Oniris, INRA, F-44300, Nantes, France., Marchand P; LABERCA, Oniris, INRA, F-44300, Nantes, France., Le Bizec B; LABERCA, Oniris, INRA, F-44300, Nantes, France., Jean-Pierre C; Toxalim, Université de Toulouse, INRA, INP-ENVT, INP-EI-Purpan, Université de Toulouse Paul Sabatier, Toulouse, France., Feidt C; URAFPA, Université de Lorraine, INRA, 2 avenue de la forêt de Haye, F-54500, Vandoeuvre, France., Vasseur P; University of Lorraine, CNRS UMR, 7360, Metz, France., Lambert M; Université Paris-Est, Anses, Laboratory for Food Safety, F-94701, Maisons-Alfort, France., Inthavong C; Université Paris-Est, Anses, Laboratory for Food Safety, F-94701, Maisons-Alfort, France., Guérin T; Université Paris-Est, Anses, Laboratory for Food Safety, F-94701, Maisons-Alfort, France., Hulin M; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 Rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France. |
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Jazyk: | angličtina |
Zdroj: | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2019 Aug; Vol. 130, pp. 308-316. Date of Electronic Publication: 2019 May 16. |
DOI: | 10.1016/j.fct.2019.05.009 |
Abstrakt: | A total diet study (TDS) was conducted between 2010 and 2016 to assess the risk associated with chemicals in food of non-breast-fed children from 1 to 36 months living in France. Food samples were collected, prepared "as consumed", and analyzed for chemicals of public health interest. Acrylamide, furan and polycyclic aromatic hydrocarbons (PAHs) were analyzed as heat-induced compounds produced mainly during thermal processing of foods. Dietary exposure was assessed for 705 representative children using food consumptions recorded through a 3-consecutive-days record. As all calculated margins of exposure (MOE) for PAHs exceeded 10 000, dietary exposure of the infant and toddler population was deemed tolerable with regard to the carcinogenic risk. Conversely, the exposure levels to acrylamide and furan were considered as of concern, requiring management measures to reduce the exposure essentially by reducing the formation of heat-induced compounds during food production or preparation processes. Efforts should mainly focus on major contributors to the exposure, i.e. sweet and savoury biscuits and bars, and potatoes and potato products for acrylamide, baby jars of vegetables, with or without meat or fish for acrylamide and furan. (Copyright © 2019 Elsevier Ltd. All rights reserved.) |
Databáze: | MEDLINE |
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