Uptake, depuration and sublethal effects of the neonicotinoid, imidacloprid, exposure in Sydney rock oysters.

Autor: Ewere EE; Marine Ecology Research Centre, Southern Cross University, PO Box 157, Lismore, NSW, 2480, Australia., Powell D; Centre for Genetics, Ecology and Physiology, University of the Sunshine Coast, Maroochydore DC, QLD, 4558, Australia; Department of Biology, Lund University, Sölvegatan 37, 223 62, Lund, Sweden., Rudd D; Drug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, 3052, Australia; Melbourne Centre for Nanofabrication, Victorian Node of the Australian National Fabrication Facility, Clayton, Victoria, 3168, Australia., Reichelt-Brushett A; Marine Ecology Research Centre, Southern Cross University, PO Box 157, Lismore, NSW, 2480, Australia., Mouatt P; Southern Cross Plant Science, Southern Cross University, PO Box 157, Lismore, NSW, 2480 Australia., Voelcker NH; Drug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, 3052, Australia; Melbourne Centre for Nanofabrication, Victorian Node of the Australian National Fabrication Facility, Clayton, Victoria, 3168, Australia., Benkendorff K; Marine Ecology Research Centre, Southern Cross University, PO Box 157, Lismore, NSW, 2480, Australia. Electronic address: kirsten.benkendorff@scu.edu.au.
Jazyk: angličtina
Zdroj: Chemosphere [Chemosphere] 2019 Sep; Vol. 230, pp. 1-13. Date of Electronic Publication: 2019 May 08.
DOI: 10.1016/j.chemosphere.2019.05.045
Abstrakt: The broad utilisation of imidacloprid (IMI) in agriculture poses an increasing risk to aquatic organisms. However, the potential impacts on commercially important shellfish and chemical residues after exposure, are yet to be assessed. We investigated the levels of IMI in Sydney rock oyster (SRO) tissue during a three-day uptake and four-day depuration cycle using liquid chromatography-mass spectrometry. IMI was absorbed from the water, with significantly higher concentrations in the adductor muscles than the gills and digestive glands. Depuration was also fast with a significant drop in tissue concentrations after one day in clean water and complete elimination from all tissues except the digestive gland after four days. The distribution of IMI in SRO after direct exposure using mass spectrometry imaging demonstrated uptake and spatially resolved metabolism to hydroxyl-IMI in the digestive gland and IMI-olefin in the gills. We assessed the effects of IMI on filtration rate (FR), acetylcholinesterase (AChE) activity in the gills, and gene expression profiles in the digestive gland using transcriptomics. Exposure to 2 mg/L IMI reduced the FR of oysters on the first day, while exposure to 0.5 and 1 mg/L reduced FR on day four. IMI reduced the gill AChE activity and altered the digestive gland gene expression profile. This study indicates that commercially farmed SRO can uptake IMI from the water, but negative impacts were only detected at concentrations higher than currently detected in estuarine environments and the chemical residues can be effectively eliminated using simple depuration in clean water.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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