| Autor: |
Guo S; Institute of Materials Research and Engineering A*STAR (Agency for Science, Technology and Research) , Innovis, #08-03, 2 Fusionpolis Way , Singapore 138634.; CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems , Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences , Shenzhen , Guangdong 518055 , China., Quintana R; Institute of Materials Research and Engineering A*STAR (Agency for Science, Technology and Research) , Innovis, #08-03, 2 Fusionpolis Way , Singapore 138634.; Materials Research and Technology Department , Luxembourg Institute of Science and Technology (LIST) , L-4422 Belvaux , Luxembourg., Cirelli M, Toa ZSD; Institute of Materials Research and Engineering A*STAR (Agency for Science, Technology and Research) , Innovis, #08-03, 2 Fusionpolis Way , Singapore 138634., Arjunan Vasantha V; Institute of Chemical and Engineering Sciences, A*STAR , 1 Pesek Road , Jurong Island, Singapore 627833., Kooij ES, Jańczewski D; Faculty of Chemistry , Warsaw University of Technology , Noakowskiego 3 , 00-664 Warsaw , Poland., Vancso GJ; Institute of Chemical and Engineering Sciences, A*STAR , 1 Pesek Road , Jurong Island, Singapore 627833. |
| Abstrakt: |
The exceptional hydration of sulfobetaine polymer brushes and their resistance toward nonspecific protein absorption allows for the construction of thin films with excellent antibiofouling properties. In this work, swollen sulfobetaine brushes, prepared by surface-initiated atom transfer radical polymerization of two monomers, differentiated by the nature of the polymerizable group, are studied and compared by a liquid-cell atomic force microscopy technique and spectroscopic ellipsometry. Colloidal AFM-based force spectroscopy is employed to estimate brush grafting density and characterize nanomechanical properties in salt water. When the ionic strength-induced swelling behaviors of the two systems are compared, the differences observed on the antipolyelectrolyte response can be correlated with the stiffness variation on brush compression, likely to be promoted by solvation differences. The higher solvation of amide groups is proposed to be responsible for the lower adhesion force of the barnacle cyprid's temporary adhesive proteins. The adhesion results provide further insights into the antibiofouling activity against barnacle cyprid settlement attributed to polysulfobetaine brushes. |
