| Autor: |
Pontes EKU; Health Sciences Center, University Center UNINTA, Sobral, CE 62050-100 Brazil., Melo HM; Health Sciences Center, University Center UNINTA, Sobral, CE 62050-100 Brazil., Nogueira JWA; Medical Sciences Center, University Center UNINTA, Sobral, CE 62050-100 Brazil., Firmino NCS; Health Sciences Center, University Center UNINTA, Sobral, CE 62050-100 Brazil., de Carvalho MG; 3Exact Sciences Center, Federal Rural University of Rio de Janeiro, Seropédica, RJ 23890-000 Brazil., Catunda Júnior FEA; Center for Exact, Natural and Technological Sciences, State University of the Tocantina Region of Maranhão, Imperatriz, MA 65901-480 Brazil., Cavalcante TTA; Medical Sciences Center, University Center UNINTA, Sobral, CE 62050-100 Brazil. |
| Abstrakt: |
Medicinal plants with antimicrobial action have been investigated for uses against biofilms, among which, Cymbopogon nardus , citronella, stands out as a promising species. The present study aims to evaluate the antimicrobial and antibiofilm action of the essential oil of C. nardus (EOCN) and geraniol on Gram-negative and positive bacteria from the determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration and inhibition of biofilms. In the results, the EOCN produced a 41 mm halo on S. aureus , which was susceptible with MIC values of 0.5 and 0.25 mg/mL for the EOCN and geraniol respectively, both with bactericidal effect. The antibiofilm action was confirmed, the EOCN and geraniol reduced the biofilm biomass of S. aureus up to 100% between 0.5 and 4 mg/mL concentrations. The reduction of cell viability was 0.25 and 1 mg/mL, of EOCN and geraniol, respectively. EOCN and geraniol were shown to be promising antibiotic against S. aureus. |
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