Characterization and comparison of strains of Pasteurella multocida associated with cases of progressive atrophic rhinitis and porcine pneumonia in Argentina.

Autor:	Bessone FA; Department of Animal Health, Instituto Nacional de Tecnología Agropecuaria, Estación Experimental Agropecuaria Marcos Juárez, Marcos Juárez, Córdoba, Argentina., Pérez MLS; Department of Animal Health, Instituto Nacional de Tecnología Agropecuaria, Estación Experimental Agropecuaria Marcos Juárez, Marcos Juárez, Córdoba, Argentina.; CONICET, Buenos Aires, Argentina., Zielinski G; Department of Animal Health, Instituto Nacional de Tecnología Agropecuaria, Estación Experimental Agropecuaria Marcos Juárez, Marcos Juárez, Córdoba, Argentina., Dibarbora M; Department of Animal Health, Instituto Nacional de Tecnología Agropecuaria, Estación Experimental Agropecuaria Marcos Juárez, Marcos Juárez, Córdoba, Argentina.; CONICET, Buenos Aires, Argentina., Conde MB; Department of Animal Health, Instituto Nacional de Tecnología Agropecuaria, Estación Experimental Agropecuaria Marcos Juárez, Marcos Juárez, Córdoba, Argentina., Cappuccio J; Department of Animal Health, Instituto Nacional de Tecnología Agropecuaria, Estación Experimental Agropecuaria Marcos Juárez, Marcos Juárez, Córdoba, Argentina.; CONICET, Buenos Aires, Argentina., Alustiza F; Department of Animal Health, Instituto Nacional de Tecnología Agropecuaria, Estación Experimental Agropecuaria Marcos Juárez, Marcos Juárez, Córdoba, Argentina.
Jazyk:	angličtina
Zdroj:	Veterinary world [Vet World] 2019; Vol. 12 (3), pp. 434-439. Date of Electronic Publication: 2019 Mar 21.
DOI:	10.14202/vetworld.2019.434-439
Abstrakt:	Background: Pasteurella multocida (Pm) is the causative agent of progressive atrophic rhinitis (PAR) and pneumonic pasteurellosis (PN) in pigs. Pm is a member of the porcine respiratory complex responsible for important economic loss in the pig industry. Aim: This study aimed to characterize the Pm strains recovered from clinical cases of PN and PAR and to elucidate the antibiotic susceptibility profiles of the strains. Materials and Methods: Sixty strains were characterized molecularly by polymerase chain reaction to determine species-specific gene, capsular type (A or D), and toxin A production. The agar diffusion method was employed to evaluate antibiotic resistance profiles. Results: We found that 65% of strains belonged to capsular type A or D, and 15% of those were positive to toxA gene. The antibiotic susceptibility profiles found were sensitive in decreasing order to: Enrofloxacin, ceftiofur (CTF), ampicillin, tilmicosin (TIL), florfenicol (FFN), spectinomycin (SPC), gentamicin, oxytetracycline (OTC), and trimethoprim-sulfamethoxazole (TMS). Strains were resistant in decreasing order to: Lincomycin (LIN), tylosin (TYL), erythromycin (ERY), TMS, SPC, OTC, FFN, TIL, and CTF. Conclusion: The toxA gene was detected in many Pm isolates from pneumonic lungs. Capsule type A or D was the most frequently found among the collected isolates. LIN, TYL, and ERY are the drugs which showed higher percentages of resistant isolates.
Databáze:	MEDLINE
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