X-chromosome data for 12 STRs: Towards an Argentinian database of forensic haplotype frequencies.

Autor: García MG; Laboratorio MANLAB, Área de Filiaciones, Buenos Aires, Argentina. Electronic address: gabriela.garcia@manlab.com.ar., Catanesi CI; Laboratorio de Diversidad Genética, Instituto Multidisciplinario de Biología Celular IMBICE, La Plata, Buenos Aires, Argentina; Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina., Penacino GA; Colegio Oficial de Farmacéuticos y Bioquímicos, Buenos Aires, Argentina; Fundación INGEN, Monte Grande, Argentina., Gusmão L; DNA Diagnostic Laboratory (LDD), State University of Rio de Janeiro (UERJ), Brazil; Institute of Pathology and Molecular Immunology from University of Porto (IPATIMUP), Portugal; Instituto de Investigação e Inovação em Saúde, I3S, Universidade do Porto, Portugal., Pinto N; Institute of Pathology and Molecular Immunology from University of Porto (IPATIMUP), Portugal; Instituto de Investigação e Inovação em Saúde, I3S, Universidade do Porto, Portugal; CMUP, Centro de Matemática da Universidade do Porto, Porto, Portugal.
Jazyk: angličtina
Zdroj: Forensic science international. Genetics [Forensic Sci Int Genet] 2019 Jul; Vol. 41, pp. e8-e13. Date of Electronic Publication: 2019 May 10.
DOI: 10.1016/j.fsigen.2019.04.005
Abstrakt: The analysis of X-chromosome STRs is useful in certain kinship cases for which autosomal markers provide insufficient statistical power. Particularly, powerful results are achieved in paternity cases with a daughter, when the alleged father is not accessible for analysis, contrarily to his unquestioned mother or daughter. However, representative haplotype frequencies for this type of markers are not available for some populations, as is the case of Argentina, which prevents the quantification of the proof in routine forensic analyses. In this work we present haplotype frequencies for the 12 X-chromosome STRs included in the Investigator Argus X-12 kit, as well as segregation data, obtained from the analysis of the genetic profiles of 457 father-daughter duos, which gave us information on 914 (unrelated) haplotypes from residents of all Argentinian provinces.
(Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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