| Autor: |
Kini H; Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India., Sreeram S; Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India., Shukla S; Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, Lucknow, India., Rao S; Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India., Sahu K; Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India., Adiga D; Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India., Suresh P; Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India. |
| Abstrakt: |
Background : Congenital pulmonary airway malformation (CPAM) is a collection of non-hereditary, developmental anomalies. Our aim was to analyze the histological profiles and prevalence of CPAMs diagnosed in our center. Methods : A retrospective study of all CPAMs diagnosed from January 1999 to May 2018 from a general hospital pathology service was performed. Results : There were 79 cystic lesions encountered in fetuses, neonates, and children, 15 of which were CPAMs {5/2372 (0.21%) autopsies and 10/216026 (0.0046%) surgical resections}. The male:female ratio was 1:1.14. Gestational age of antenatal cases ranged from 22 to 32 weeks, postnatal ages ranged from 7 days to 15 years (mean 2.9 years). The cases were right-sided (8/15;53.3%), left-sided (4/15;26.7%) and bilateral (3/15,20%). Seven (46.7%), 4 (26.7%),3 (20%) and 1 (6.7%) were types 1, 2, 3 and 4, respectively. None of the surgical cases had postoperative mortality or morbidity. Conclusions : Prompt recognition and surgical resectability resulted in normal growth and symptom free survival in our postnatally diagnosed patients. Mortality in antenatally diagnosed fetuses remains high (5/11;45%). |
