Antimicrobial potential of aqueous extract of Camellia sinensis against representative microbes.

Autor:	Khan I; Food Safety Research Group, Lab # 115, Department of Microbiology, Faculty of Science, University of Karachi, Karachi, Pakistan / Department of Microbiology, Faculty of Science, University of Karachi, Karachi, Pakistan., Abbas T; Food Safety Research Group, Lab # 115, Department of Microbiology, Faculty of Science, University of Karachi, Karachi, Pakistan / Department of Microbiology, Faculty of Science, University of Karachi, Karachi, Pakistan., Anjum K; Food Safety Research Group, Lab # 115, Department of Microbiology, Faculty of Science, University of Karachi, Karachi, Pakistan / Department of Microbiology, Faculty of Science, University of Karachi, Karachi, Pakistan / Ocean College, Zhejiang University, Hangzhou, China., Abbas SQ; Gomal University, DI Khan, KPK, Pakistan., Shagufta BI; Department of Zoology, Kohat University of Science and Technology, KPK, Pakistan., Shah SAA; Ocean College, Zhejiang University, Hangzhou, China., Akhter N; Ocean College, Zhejiang University, Hangzhou, China., Hassan SS; Ocean College, Zhejiang University, Hangzhou, China / Gomal University, DI Khan, KPK, Pakistan.
Jazyk:	angličtina
Zdroj:	Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2019 Mar; Vol. 32 (2), pp. 631-636.
Abstrakt:	Camellia sinensis is being used for decades for its therapeutic efficacies against physiological problems and microbial infections. This study was undertaken to investigate the antibacterial and antifungal potential of aqueous extract of Camellia sinensis. Antibacterial activity was determined by disc and well diffusion assay. MIC and MBC were calculated by broth dilution method. Miles and Misra technique was used to find out colony forming unit per/ml. All the test organisms revealed a diverse range of vulnerability against aqueous extract. Among Gram positive, MRSA showed to be the most sensitive with least MIC and MBC while among Gram-negative Pseudomonas aeruginosa exhibited the highest sensitivity. In Miles and Misra, a progressive decline in log of CFU/ml was observed. In time-kill assay, a decline was noted in the viable count of S.aureus after exposure to 18% aqueous extract of Camellia sinensis. In the present study aqueous extract of Camellia sinensis found to be effective against Gram positive, Gram negative and fungi. The most important finding of this study is its aqueous extract inhibitory effect against drug-resistant microorganisms e.g. MRSA and P. aeruginosa and Candida albicans.
Databáze:	MEDLINE
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