| Autor: |
Horiuchi M; Department of Hematology, Osaka City General Hospital., Nakao T; Department of Hematology, Osaka City General Hospital., Tsutsumi M; Department of Hematology, Osaka City General Hospital., Nakaya Y; Department of Hematology, Osaka City General Hospital., Fuseya H; Department of Hematology, Osaka City General Hospital., Yoshida M; Department of Hematology, Osaka City General Hospital., Yoshimura T; Department of Hematology, Osaka City General Hospital., Hayashi Y; Department of Hematology, Osaka City General Hospital., Fukushima H; Department of Pathology, Osaka City General Hospital., Inoue T; Department of Pathology, Osaka City General Hospital., Yamane T; Department of Hematology, Osaka City General Hospital. |
| Jazyk: |
japonština |
| Zdroj: |
[Rinsho ketsueki] The Japanese journal of clinical hematology [Rinsho Ketsueki] 2019; Vol. 60 (3), pp. 218-222. |
| DOI: |
10.11406/rinketsu.60.218 |
| Abstrakt: |
Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin lymphoma, usually presenting as serous effusions without detectable tumor masses, and it is universally associated with the human herpesvirus 8 (HHV8). In contrast, cases of HHV8-negative effusion lymphoma have been reported and termed as HHV8-negative PEL-like lymphoma. Here, we have reported a rare case of HHV8-negative PEL-like lymphoma that developed in the left atrium tumor 4 years after the pericardial drainage. A 74-year-old female was admitted due to cardiac tamponade caused by massive pericardial effusion. Pericardial drainage was performed, and cytopathologic examination of the fluid revealed atypical lymphoid cells consistent with an effusion lymphoma of B-cell lineage. The pericardial effusion was completely drained, and complete remission was achieved. After 4 years of the drainage, she developed syncope caused by arrhythmia. A computed tomography scan revealed a large tumor in the left atrium and multiple swollen mediastinal lymph nodes. Biopsy of one of the lymph nodes was performed, and its histology was consistent with diffuse large B-cell lymphoma. She was treated with chemotherapy, including rituximab, and complete remission was achieved again. Thus, our experience suggests that careful follow-up may be required in patients with HHV8-negative PEL-like lymphoma after complete remission has been achieved by the drainage. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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