Familial aggregation and heritability of markers of metabolic risk, physical activity, and physical fitness in nuclear families from Muzambinho (Minas Gerais, Brazil).

Autor:	Barbosa JPDAS; Laboratório de Hemodinâmica da Atividade Motora, Escola de Educação Física e Esporte, Universidade de São Paulo, SP, Brasil., Basso L; Laboratório de Comportamento Motor, Escola de Educação Física e Esporte, Universidade de São Paulo, SP, Brasil., Bartholomeu T; Laboratório de Hemodinâmica da Atividade Motora, Escola de Educação Física e Esporte, Universidade de São Paulo, SP, Brasil., Rezende JAS; Instituto Federal do Sul de Minas - Campus Muzambinho, Muzambinho, MG, Brasil., Oliveira JA; Laboratório de Comportamento Motor, Escola de Educação Física e Esporte, Universidade de São Paulo, SP, Brasil., Prista A; Núcleo de Investigação em Actividade Física e Saúde, Centro de Investigação e Desenvolvimento do Desporto e Actividade Física (CIDAF), Faculdade de Educação Física e Desporto (FEFD), Universidade Pedagógica, Maputo, Moçambique., Tani G; Laboratório de Comportamento Motor, Escola de Educação Física e Esporte, Universidade de São Paulo, SP, Brasil., Maia JAR; Laboratório de Cineantropometria e Gabinete de Estatística Aplicada, Centro de Investigação, Formação, Intervenção e Inovação em Desporto (CIFI2D), Faculdade de Desporto, Universidade do Porto, Porto, Portugal., Forjaz CLM; Laboratório de Hemodinâmica da Atividade Motora, Escola de Educação Física e Esporte, Universidade de São Paulo, SP, Brasil.
Jazyk:	angličtina
Zdroj:	Archives of endocrinology and metabolism [Arch Endocrinol Metab] 2019 May-Jun; Vol. 63 (3), pp. 215-221. Date of Electronic Publication: 2019 May 02.
DOI:	10.20945/2359-3997000000137
Abstrakt:	Objective: This study investigated the familial aggregation and heritability of markers of metabolic risk, physical activity, and physical fitness in nuclear families from Muzambinho (Minas Gerais, Brazil). Subjects and Methods: The study included members of 139 families, comprising 97 fathers (aged 40 ± 7 years), 129 mothers (35 ± 6 years), 136 sons (12 ± 4 years), and 121 daughters (12 ± 5 years). Evaluated markers included (A) body mass index, waist circumference, glycemia, and cholesterolemia, as metabolic risk markers; (B) total weekly volume of physical activity, as a physical activity marker; and (C) relative muscle strength, as a physical fitness marker. Correlations between family members and heritability (h2) were estimated using the software S.A.G.E. Results: Significant familial correlations were obtained between parents-offspring for glycemia and cholesterolemia (both ρ = 0.21, p < 0.05) and relative muscle strength (ρ = 0.23, p < 0.05), and between siblings for waist circumference, glycemia, total weekly volume of physical activity, and relative muscle strength (ρ variation 0.25 to 0.36, p < 0.05). Heritability values were significant for almost all variables (h2 variations: 20% to 57% for metabolic risk markers, 22% for the total weekly volume of physical activity, and 50% for relative muscle strength), except for waist circumference (h2 = 15%, p = 0.059). Conclusion: The presence of significant correlations between family members and/or significant heritability strengthens the possible genetic and/or common familial environment influence on metabolic risk markers, total weekly volume of physical activity, and relative muscle strength.
Databáze:	MEDLINE
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