| Autor: |
Esper HR; Hospital Municipal, Santarém, Pará, Brazil.; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil., Freitas VLT; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil., Assy JGPL; Hospital Municipal, Santarém, Pará, Brazil.; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil., Shimoda EY; Universidade de São Paulo, Hospital das Clínicas, Laboratório de Investigação Médica em Imunologia (LIM 48), São Paulo, São Paulo, Brazil., Berreta OCP; Hospital Municipal, Santarém, Pará, Brazil.; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil., Lopes MH; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil.; Universidade de São Paulo, Hospital das Clínicas, Laboratório de Investigação Médica em Imunologia (LIM 48), São Paulo, São Paulo, Brazil., França FOS; Universidade de São Paulo, Faculdade de Medicina, São Paulo, São Paulo, Brazil.; Universidade de São Paulo, Hospital das Clínicas, Laboratório de Investigação Médica em Imunologia (LIM 48), São Paulo, São Paulo, Brazil. |
| Abstrakt: |
Trypanosoma cruzi is the causative agent of Chagas disease. Nowadays, the transmission in Brazil occurs mainly by oral ingestion of contaminated food that has been associated with more severe clinical manifestations. We report a case of Acute Chagas disease caused by oral transmission in a child from Northern Brazil. In the hospital admission, physical examination showed tachycardia, hepatomegaly, bipalpebral edema and anasarca. Trypanosoma cruzi trypomastigotes were found in microscopy during blood cell count. Twenty-three days before hospitalization, the child had ingested the "bacaba palm fruit's wine". Even with the appropriate diagnosis and starting of treatment, she did not survive. Quantitative analysis of Trypanosoma cruzi DNA in a blood sample resulted in 54,053.42 parasite equivalents/mL and the DTU TcIV was identified. The outcome may have been determined by several factors, including the delay to seek a medical service beyond the high parasitemia, detected by qPCR. DTU TcIV could also have influenced the natural history of the disease. |
