Incidence and characteristics of Lyme neuroborreliosis in adult patients with facial palsy in an endemic area in the Netherlands.

Autor: Bierman SM; Lyme Centre Apeldoorn, Gelre Hospital,Apeldoorn,The Netherlands., van Kooten B; Lyme Centre Apeldoorn, Gelre Hospital,Apeldoorn,The Netherlands., Vermeeren YM; Lyme Centre Apeldoorn, Gelre Hospital,Apeldoorn,The Netherlands., Bruintjes TD; Department of Otorhinolaryngology,Gelre Hospital,Apeldoorn,The Netherlands., van Hees BC; Lyme Centre Apeldoorn, Gelre Hospital,Apeldoorn,The Netherlands., Bruinsma RA; Lyme Centre Apeldoorn, Gelre Hospital,Apeldoorn,The Netherlands., Landman GW; Lyme Centre Apeldoorn, Gelre Hospital,Apeldoorn,The Netherlands., van Bemmel T; Lyme Centre Apeldoorn, Gelre Hospital,Apeldoorn,The Netherlands., Zomer TP; Lyme Centre Apeldoorn, Gelre Hospital,Apeldoorn,The Netherlands.
Jazyk: angličtina
Zdroj: Epidemiology and infection [Epidemiol Infect] 2019 Jan; Vol. 147, pp. e160.
DOI: 10.1017/S0950268819000438
Abstrakt: Making a distinction between facial palsy due to Lyme neuroborreliosis (LNB) and idiopathic facial palsy (IFP) is of importance to ensure timely and adequate treatment. The study objective was to assess incidence and patient characteristics of facial palsy due to LNB. Hospital records were reviewed of adult patients with facial palsy visiting the departments of neurology and/or otorhinolaryngology of Gelre hospitals between June 2007 and December 2017. Gelre hospitals are located in an area endemic for Lyme borreliosis. Patients with LNB had pleocytosis and intrathecal antibody production or pleocytosis with positive IgG serology. Patients with IFP had negative serology. Clinical characteristics were compared between patients with LNB and patients with IFP. Five hundred and fifty-nine patients presented with facial palsy, 4.7% (26) had LNB and 39.4% (220) IFP. The incidence of facial palsy due to LNB was 0.9/100 000 inhabitants/year. Over 70% of patients with facial palsy due to LNB did not report a recent tick bite and/or erythema migrans (EM). Patients with facial palsy due to LNB presented more often in July to September (69.2% vs. 21.9%, P < 0.001), and had more often headache (42.3% vs. 15.5%, P < 0.01). To reduce the risk of underdiagnosing LNB in an endemic area, we recommend testing for LNB in patients with facial palsy in summer months especially when presenting with headache, irrespective of a recent tick bite and/or EM.
Databáze: MEDLINE