Radiation Therapy and its Effects Beyond the Primary Target: An Abscopal Effect.

Autor: Wani SQ; Radiation Oncology, Sher I Kashmir Institute of Medical Sciences, Srinagar, IND., Dar IA; Radiation Oncology, Sher I Kashmir Institute of Medical Sciences, Srinagar, IND., Khan T; Anesthesiology, Sher I Kashmir Institute of Medical Sciences, Srinagar, IND., Lone MM; Radiation Oncology, Sher I Kashmir Institute of Medical Sciences, Srinagar, IND., Afroz F; Radiation Oncology, Sher I Kashmir Institute of Medical Sciences, Srinagar, IND.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2019 Feb 19; Vol. 11 (2), pp. e4100. Date of Electronic Publication: 2019 Feb 19.
DOI: 10.7759/cureus.4100
Abstrakt: Radiation therapy (RT) has been used for the treatment of various malignancies since decades with curative or palliative intent. RT for primary disease is often used with curative intent while its use in metastatic settings has been essentially palliative. However, in certain malignancies with metastatic disease, RT to primary disease has led to the regression of not only the primary site but also of the metastatic sites, a phenomenon known as "abscopal effect." Keeping in view the positive effects of RT beyond the primary site, we review the clinical utility of RT regarding its abscopal effect.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE