Comparative Assessment of Some White Blood Cell and Platelet Parameters among Normotensive and Hypertensive Subjects in Port Harcourt, Nigeria.

Autor: Eziuzo CI; Department of Human Physiology, Haemorheology and Immunology Research Unit, College of Health Sciences, University of Port Harcourt, Port Harcourt, Nigeria., Chinko BC; Department of Human Physiology, Haemorheology and Immunology Research Unit, College of Health Sciences, University of Port Harcourt, Port Harcourt, Nigeria., Dapper DV; Department of Human Physiology, Haemorheology and Immunology Research Unit, College of Health Sciences, University of Port Harcourt, Port Harcourt, Nigeria.
Jazyk: angličtina
Zdroj: Nigerian medical journal : journal of the Nigeria Medical Association [Niger Med J] 2017 Jul-Aug; Vol. 58 (4), pp. 131-137.
DOI: 10.4103/nmj.NMJ_25_17
Abstrakt: Background: Reports comparing the values of white blood cells (WBCs) and platelet parameters among normotensive, newly diagnosed hypertensive, and known hypertensive participants in Nigeria are relatively scarce. This study sought to compare these hematologic parameters of normotensive and hypertensive participants in the Southeastern Nigeria.
Materials and Methods: Fifty participants each of normotensive, newly diagnosed hypertensive, and known hypertensive and age- and sex-matched individuals were recruited into the study. Using an automated hematology analyzer, the following hematological parameters were determined in all participants: total WBC; neutrophil, lymphocyte and platelet counts; percentage value of neutrophil and lymphocytes; mean platelet volume (MPV); platelet distribution width; and total lymphocyte count.
Results: Significantly higher total WBCs and (absolute) neutrophil counts and lower percentage lymphocyte were observed among known hypertensive male participants, whereas percentage neutrophil was significantly higher among known hypertensive female participants. Platelet count and MPV were significantly higher in hypertensive male participants compared to their normotensive counterparts. MPV was found to be significantly lower in hypertensive female participants compared to normotensive females.
Conclusion: The present study reports significantly higher leukocytes, platelet counts, and MPV among hypertensive males and lower MPV among hypertensive females. Regular assessment of hematological parameters may perhaps be useful indicators of the prognosis of hypertension among the study population.
Competing Interests: There are no conflicts of interest.
Databáze: MEDLINE
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