Animal Experiments in Periodontal and Peri-Implant Research: Are There Any Changes?

Autor: Staubli N; Department of Periodontology, Endodontology and Cariology, University Centre for Dental Medicine, University of Basel, Hebelstrasse 3, 4056 Basel, Switzerland. noemi.staubli@unibas.ch., Schmidt JC; Department of Periodontology, Endodontology and Cariology, University Centre for Dental Medicine, University of Basel, Hebelstrasse 3, 4056 Basel, Switzerland. julia.schmidt@unibas.ch., Rinne CA; Department of Periodontology, Endodontology and Cariology, University Centre for Dental Medicine, University of Basel, Hebelstrasse 3, 4056 Basel, Switzerland. carin.rinne@unibas.ch., Signer-Buset SL; Private Dental Office Grimm Zahnärzte, Horgen, Schweiz, 8810 Basel, Switzerland. sbuset@gmx.ch., Rodriguez FR; Private Dental Office Dentilus AG, Forchstrasse 99, 8032 Zurich, Switzerland. FabRod@gmx-topmail.de., Walter C; Department of Periodontology, Endodontology and Cariology, University Centre for Dental Medicine, University of Basel, Hebelstrasse 3, 4056 Basel, Switzerland. clemens.walter@unibas.ch.
Jazyk: angličtina
Zdroj: Dentistry journal [Dent J (Basel)] 2019 May 01; Vol. 7 (2). Date of Electronic Publication: 2019 May 01.
DOI: 10.3390/dj7020046
Abstrakt: Animal experiments are a source of debate. This bibliometric study aims to identify published research in two representative dental journals: the Journal of Periodontology (JP) and the Journal of Clinical Periodontology (JCP). Two time points (1982/83 and 2012/13) covering 30 years were chosen. Articles describing data from animal experiments were identified and the data were extracted and compared between journals and time points. In 1982/83, 27 animal studies were published in JP and 17 in JCP. For 2012/13, 54 animal studies were considered in JP and 37 in JCP. The species examined were predominantly dogs (37%) in JCP and rats (61%) in JP in 1982/83. In 2012/13, rodents accounted for 85% in JP and for 54% in JCP. The number of animals used per study increased by a factor of 1.6-2.6. The diversity of geographic origin and articles from emerging countries increased over time. The number of animals examined per study and the publications describing these experiments seemed to have increased in the journals analyzed in the last decades.
Databáze: MEDLINE