Ancestry Tracing: Uncovering a Gliomagenesis Master Regulator.
| Autor: | Floriddia EM; Laboratory of Molecular Neurobiology, Department of Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Castelo-Branco G; Laboratory of Molecular Neurobiology, Department of Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden; Ming Wai Lau Centre for Reparative Medicine, Stockholm node, Karolinska Institutet, Stockholm, Sweden. Electronic address: goncalo.castelo-branco@ki.se. |
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| Jazyk: | angličtina |
| Zdroj: | Cell stem cell [Cell Stem Cell] 2019 May 02; Vol. 24 (5), pp. 677-679. |
| DOI: | 10.1016/j.stem.2019.04.006 |
| Abstrakt: | In this issue of Cell Stem Cell, Weng et al. (2019) characterize a progenitor population that precedes oligodendrocyte progenitor cells (OPCs). The authors identified Zfp36l1 as a key regulator of the cell fate switch between oligodendrocytes and astrocytes in neural progenitors, and thereby an important regulator of cellular processes such as myelination and gliomagenesis. (Copyright © 2019 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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