An Uncommon Case of Ectopic Adrenocorticotropic Hormone Syndrome from a Pancreatic Neuroendocrine Tumor.

Autor: Wang W; Internal Medicine, Florida Hospital, Orlando, USA., Miao R; Internal Medicine, Florida Hospital, Orlando, USA., Zhang L; Internal Medicine, Florida Hospital, Orlando, USA., Hasan SA; Internal Medicine, Florida Hospital, Orlando, USA., Bakhtiani P; Internal Medicine, Florida Hospital, Orlando, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2019 Feb 14; Vol. 11 (2), pp. e4076. Date of Electronic Publication: 2019 Feb 14.
DOI: 10.7759/cureus.4076
Abstrakt: Ectopic adrenocorticotropic hormone (ACTH) syndrome is a rare form of Cushing disease (CD) with over-secretion of ACTH from nonpituitary tumor outside the adrenal or pituitary glands. Its diagnosis relies on both biochemical tests (high-dose dexamethasone suppression test, ACTH level, corticotropin-releasing hormone test) to confirm ACTH-dependent CD and image studies (CT or MRI of chest, abdomen, and/or pelvis) for source localization. We present a rare case of ectopic ACTH syndrome from a pancreatic neuroendocrine tumor (NET).
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE