Profile of Pregnant Women with Gestational Diabetes Mellitus at Increased Risk for Large for Gestational Age Newborns.
| Autor: | Tavares MDGR; Endocrinology Unit of University Hospital, Universidade Federal do Maranhão, São Luís, MA, Brazil., Lopes ÉS; Endocrinology Unit of University Hospital, Universidade Federal do Maranhão, São Luís, MA, Brazil., Barros RAJPA; Department of Obstetrics and Gynecology, Universidade Federal do Maranhão, São Luís, MA, Brazil., Azulay RSS; Endocrinology Unit of University Hospital, Universidade Federal do Maranhão, São Luís, MA, Brazil., Faria MDS; Endocrinology Unit of University Hospital, Universidade Federal do Maranhão, São Luís, MA, Brazil. |
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| Jazyk: | angličtina |
| Zdroj: | Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia [Rev Bras Ginecol Obstet] 2019 May; Vol. 41 (5), pp. 298-305. Date of Electronic Publication: 2019 Apr 24. |
| DOI: | 10.1055/s-0039-1687860 |
| Abstrakt: | Objective: Gestational diabetes mellitus (GDM) is associated with a higher risk of perinatal morbidity and mortality, and its main complication is the occurrence of large for gestational age (LGA) newborns. The present study aims to characterize pregnant women with GDM and to identify factors associated with the occurrence of LGA newborns in this population. Methods: A cross-sectional study was performed based on medical records of women whose prenatal care and delivery were performed at the Maternal and Child Unit of the Hospital Universitário of the Universidade Federal do Maranhão, state of Maranhão, Brazil. A total of 116 pregnant women diagnosed with GDM were included according to the criteria of the International Association of Diabetes and Pregnancy Study Groups (IADPSG). Results: The variables associated with LGA newborns after multivariate analysis were: obesity prior to pregnancy (OR = 11.6; 95% CI: 1.40-95.9), previous macrosomia (OR = 34.7; 95% CI: 4.08-295.3), high blood glucose levels in the 3 rd trimester (OR = 2,67; 95% CI: 1.01-7.12) and combined change in the oral glucose tolerance test (OGTT) (fasting + postdextrose) (OR = 3.53; 95% CI: 1.25-14.2) = 1.17-10.6). Otherwise, insufficient weight gain during pregnancy reduced the risk for LGA newborns (OR = 0.04; 95% CI: 0.01-0.32). Conclusion: Obesity prior to pregnancy, previous macrosomia, high blood glucose levels in the 3 rd trimester, and combined change in the OGTT were independent predictive factors for LGA newborns in pregnant women with GDM. Competing Interests: The authors have no conflicts of interests to declare. (Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil.) |
| Databáze: | MEDLINE |
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