Tetrasomy 8 Associated with a Poor Prognosis in Acute Monoblastic Leukemia: A Case Report.
| Autor: | Farag F; Internal Medicine, Brookdale University Hospital and Medical Center, Brooklyn, USA., Morcus R; Internal Medicine, Brookdale University Hospital and Medical Center, Brooklyn, USA., Ramachandran P; Oncology, Brookdale University Hospital and Medical Center, Brooklyn, USA., Josan K; Oncology, Brookdale University Hospital and Medical Center, Brooklyn, USA., Wang JC; Oncology, Brookdale University Hospital and Medical Center, Brooklyn, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2019 Feb 13; Vol. 11 (2), pp. e4068. Date of Electronic Publication: 2019 Feb 13. |
| DOI: | 10.7759/cureus.4068 |
| Abstrakt: | We report a case of a 47-year-old male from West Africa who presented with sepsis and was found to have acute monoblastic leukemia associated with tetrasomy 8 detected on bone marrow samples. This was the only chromosomal abnormality found. Tetrasomy 8 is a rare genetic finding that has been reported in acute myeloid leukemia (AML), predominantly the monocytic lineage. It carries a poor prognosis with a high mortality rate. Competing Interests: The authors have declared that no competing interests exist. |
| Databáze: | MEDLINE |
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