Tortuosity of the descending thoracic aorta: Normal values by age.

Autor: Belvroy VM; Thoracic Aortic Research Center, IRCCS Policlinico San Donato, San Donato Milanese, Italy.; Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, Netherlands.; Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, United States of America., de Beaufort HWL; Thoracic Aortic Research Center, IRCCS Policlinico San Donato, San Donato Milanese, Italy.; Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, Netherlands., van Herwaarden JA; Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, Netherlands., Bismuth J; Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, United States of America., Moll FL; Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, Netherlands., Trimarchi S; Department of Health and Community Sciences, University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan, Milan, Italy.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2019 Apr 23; Vol. 14 (4), pp. e0215549. Date of Electronic Publication: 2019 Apr 23 (Print Publication: 2019).
DOI: 10.1371/journal.pone.0215549
Abstrakt: Background: Aging changes the aorta in length, tortuosity and diameter. This is relevant in thoracic endovascular aortic repair (TEVAR) and in the long term follow up.
Methods and Results: Two groups of hundred patients < 65 years and hundred patients ≥ 65 years, with no vascular diseases were made. Thin cut CT scans were analyzed with 3Mensio Vascular software and the following measurements were collected; tortuosity index, curvature ratio, maximum tortuosity in degrees and the level of vertebrae of the maximum tortuosity. The descending thoracic aorta (DTA) was analyzed and was divided into four zones of equal length. Subjects were divided into three groups based on their maximum tortuosity value: low (< 30°), moderate (30° - 60°) and high (> 60°). A linear regression model was built to test the effect of age and gender on tortuosity. Tortuosity was more pronounced in the ≥ 65 compared to the < 65 group (tortuosity index: 1.05 vs. 1.14, respectively; p < 0.001), curvature ratio (1.00 vs. 1.01; p < 0.001), maximum tortuosity (22.24 vs. 27.26; p < 0.001), and group of angulation (low vs. low; p < 0.001). Additionally, the location of maximum tortuosity was further distal for the ≥ 65 group (level of vertebrae; 5.00 vs. 5.00; p < 0.001), and zone of maximum tortuosity (4A vs. 4A; p < 0.001). There was no significant difference between male and female subjects.
Conclusion: Normal DTA tortuosity increases with age. This is important to understand natural aging and for TEVAR planning and follow-up.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
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