[Substantion of the reference Values of SCFA in saliva in ratients without upper respiratory tract diseases.]
| Autor: | Zatevalov AM; G.N. Gabrichevsky research institute for epidemiology and microbiology, Rospotrebnadzor, 125212, Moscow, Russia., Gudova NV; G.N. Gabrichevsky research institute for epidemiology and microbiology, Rospotrebnadzor, 125212, Moscow, Russia., Oganesyan AS; G.N. Gabrichevsky research institute for epidemiology and microbiology, Rospotrebnadzor, 125212, Moscow, Russia., Selkova EP; G.N. Gabrichevsky research institute for epidemiology and microbiology, Rospotrebnadzor, 125212, Moscow, Russia., Mironov AY; G.N. Gabrichevsky research institute for epidemiology and microbiology, Rospotrebnadzor, 125212, Moscow, Russia., Grechishnikova OG; G.N. Gabrichevsky research institute for epidemiology and microbiology, Rospotrebnadzor, 125212, Moscow, Russia. |
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| Jazyk: | ruština |
| Zdroj: | Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2019; Vol. 64 (3), pp. 153-157. |
| DOI: | 10.18821/0869-2084-2019-64-3-153-157 |
| Abstrakt: | Biochemical indicators of saliva were studied in 47 patients of the intensive care unit and intensive care unit of a neurosurgical hospital with varying degrees of severity of the disease. The method of gas-liquid chromatography of the acidified substrate of the saliva filtrate determined the concentrations of short-chain fatty acids (SCFA) and their reference values for patients without respiratory tract diseases. The threshold values of the concentrations of SCFA and the values of their calculated indices were determined by ROC analysis with the construction of the ROC curve, calculation of the area under the curve (AUC) and the cutoff threshold CutOff. The method of determining reference values of HFA in saliva developed as a result of the study makes it possible to assess the risks of developing an unfavorable course of the disease, optimize treatment tactics and improve the prognosis of the disease. Competing Interests: The authors declare no conflict of interest. |
| Databáze: | MEDLINE |
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