[Diffusion tensor imaging and visual evoked potentials in pediatric patients with sellar region lesions].

Autor:	Luo B; School of Clinical Medicine, Tsinghua University, Beijing 100084, China., Miao SH; Department of Neurosurgery, Tsinghua University Yuquan Hospital, Beijing 100049, China., He L; Center for Biomedical Imaging Research, Tsinghua University, Beijing 100084, China., Zhao YP; School of Clinical Medicine, Tsinghua University, Beijing 100084, China., Xu CW; School of Clinical Medicine, Tsinghua University, Beijing 100084, China., Zhu J; School of Clinical Medicine, Tsinghua University, Beijing 100084, China., Zhang QH; School of Clinical Medicine, Tsinghua University, Beijing 100084, China., Liu W; School of Clinical Medicine, Tsinghua University, Beijing 100084, China., Ma Y; Department of Neurosurgery, Tsinghua University Yuquan Hospital, Beijing 100049, China., Zhang YQ; Department of Neurosurgery, Tsinghua University Yuquan Hospital, Beijing 100049, China.
Jazyk:	čínština
Zdroj:	Zhonghua yi xue za zhi [Zhonghua Yi Xue Za Zhi] 2019 Apr 16; Vol. 99 (15), pp. 1167-1171.
DOI:	10.3760/cma.j.issn.0376-2491.2019.15.010
Abstrakt:	Objiective: To evaluate the prognosis of visual function and the impact of surgery in pediatric patients with sellar mass lesions, as evidenced by diffusion tensor imaging (DTI) and visual evoked potentials. Methods: Twenty patients with sellar mass lesions were included in the study. DTI and visual evoked potentials were obtained before and after surgery. Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values were calculated for both optic nerves. DTI parameters and visual evoked potential amplitudes were compared for all patients to assess the correlation between DTI parameters and visual function. Results: The 20 patients were divided into two groups according the relationship between the lesions and the optic chiasm. The FA values increased significantly after operation, while the ADC values decreased ( P <0.05). And the average amplitude of visual evoked potentials after operation was significantly higher than before operation ( P< 0.05). Conclusions: DTI assessments of the affected sides, with the resulting FA and ADC values, may help to estimate the visual improvement produced by surgical therapy in the early postoperative period. Surgical removal can improve visual function dramatically.
Databáze:	MEDLINE
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