Health benefits of subcutaneous zinc edetate and diphenyl diselenide in calves during the weaning period.

Autor: Santos DSD; Departamento de Zootecnia, Universidade do Estado de Santa Catarina/UDESC, Rua Beloni Trombeta Zanin, 680D, 89815-630 Chapecó, SC, Brazil., Boito JP; Departamento de Zootecnia, Universidade do Estado de Santa Catarina/UDESC, Rua Beloni Trombeta Zanin, 680D, 89815-630 Chapecó, SC, Brazil., Klauck V; Programa de Pós-Graduação em Zootecnia, Universidade do Estado de Santa Catarina/UDESC, Rua Beloni Trombeta Zanin, 680D, 89815-630 Chapecó, SC, Brazil., Reis JHD; Departamento de Zootecnia, Universidade do Estado de Santa Catarina/UDESC, Rua Beloni Trombeta Zanin, 680D, 89815-630 Chapecó, SC, Brazil., Gebert RR; Departamento de Zootecnia, Universidade do Estado de Santa Catarina/UDESC, Rua Beloni Trombeta Zanin, 680D, 89815-630 Chapecó, SC, Brazil., Glombowsky P; Departamento de Zootecnia, Universidade do Estado de Santa Catarina/UDESC, Rua Beloni Trombeta Zanin, 680D, 89815-630 Chapecó, SC, Brazil., Biazus AH; Programa de Pós-Graduação em Zootecnia, Universidade do Estado de Santa Catarina/UDESC, Rua Beloni Trombeta Zanin, 680D, 89815-630 Chapecó, SC, Brazil., Bottari NB; Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria/UFSM, Avenida Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Sousa RS; Departamento de Bioquímica e Biologia Molecular, Universidade de São Paulo/USP, Avenida Prof. Lineu Prestes, 748, 05508-000 São Paulo, SP, Brazil., Machado G; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Gortner Ave, 1365, St. Paul, 55108 MN, USA., Leal MLR; Departamento de Grandes Animais, Universidade Federal de Santa Maria/UFSM, Avenida Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Baldissera MD; Departamento de Microbiologia e Parasitologia, Universidade Federal de Santa Maria/UFSM, Avenida Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Berwanger JC; Graduação em Medicina Veterinária, Universidade Norte do Paraná/UNOPAR, Avenida Paris, Jardim Piza, 675, 86083-070 Londrina, PR, Brazil., Silva ASD; Departamento de Zootecnia, Universidade do Estado de Santa Catarina/UDESC, Rua Beloni Trombeta Zanin, 680D, 89815-630 Chapecó, SC, Brazil.; Programa de Pós-Graduação em Zootecnia, Universidade do Estado de Santa Catarina/UDESC, Rua Beloni Trombeta Zanin, 680D, 89815-630 Chapecó, SC, Brazil.
Jazyk: angličtina
Zdroj: Anais da Academia Brasileira de Ciencias [An Acad Bras Cienc] 2019; Vol. 91 (1), pp. e20171042. Date of Electronic Publication: 2019 Apr 08.
DOI: 10.1590/0001-3765201920171042
Abstrakt: The aims of this study were to investigate whether treatments with zinc edetate (Zn) and diphenyl diselenide ((PhSe)2) enhance performance, immune responses, protein metabolism, and oxidant/antioxidant status in calf serum and muscle. Animals were divided into four groups (n=6 each): control (without supplementation), and groups supplemented on days 50 and 70 of life with (PhSe)2, Zn, and a combination of (PhSe)2 and Zn. Animals treated with (PhSe)2 gained more weight by experimental day 220 than did the control group, but there was no difference by the end of the experiment (day 300). The absolute number of leukocytes and lymphocytes increased in groups Zn and (PhSe)2+Zn on day 20 of experiment, but decreased on day 40 in groups (PhSe)2, and (PhSe)2+Zn. The number of monocytes decreased in all groups compared with control. One of the principal findings was that (PhSe)2+Zn together had beneficial effects on protein metabolism, represented by increases total protein and globulin levels, compared with the control group. The combination of (PhSe)2 and Zn led to low levels of TBARS and ROS in serum and muscle, and stimulated antioxidant enzyme activities. Thus, supplementation with (PhSe)2+Zn may be a compelling approach to augmenting the calf antioxidant system during weaning.
Databáze: MEDLINE
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