Blood donor safety, prevalence and associated factors for cytomegalovirus infection among blood donors in Minna-Nigeria, 2014.

Autor:	Bawa MK; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Mamman A; Ahmadu Bello University, Zaria, Nigeria., Olayinka A; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria.; Ahmadu Bello University, Zaria, Nigeria., Gidado S; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Waziri NE; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Balogun MS; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Getso KI; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria.; Ministry of Health, Kano, Nigeria., Dalhat MM; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Nsubuga P; Global Public Health Solutions, Atlanta GA, USA., Aliyu N; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Bala H; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Muhammad H; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Haladu S; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Shehu UL; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria., Nguku PM; Nigeria Field Epidemiology and Laboratory Training Program, Abuja-Nigeria.
Jazyk:	angličtina
Zdroj:	The Pan African medical journal [Pan Afr Med J] 2019 Jan 22; Vol. 32 (Suppl 1), pp. 6. Date of Electronic Publication: 2019 Jan 22 (Print Publication: 2019).
DOI:	10.11604/pamj.supp.2019.32.1.13297
Abstrakt:	Introduction: human cytomegalovirus (CMV) has remained a cause of morbidity and mortality in pregnancy and immunocompromised patients. CMV is transmissible through blood transfusion. We conducted a descriptive, cross-sectional study to assess blood donor safety and to determine the prevalence and associated factors for CMV infection among blood donors in Minna, Nigeria. Methods: all consenting blood donors were screened for CMV antibodies (IgM and IgG) using ELISA kit and haematological indices using a haematological analyzer. We administered structured questionnaires to obtain socio-demographic and socio-economic data. Data were subjected to univariate, bivariate and multivariate statistical analyses using Epi Info version 3.5.4. Significant associations were presumed if p < 0.05. Results: a total of 345 participantswere recruited, the majority were males 336 (97.4%). Monthly earnings of majority of the blood donors, 136 (40.6%) ranged from ₦18,000 to ₦35,000. The prevalence of CMV infection was 96.2%. The prevalence of anti-CMV IgG antibodies was 96.2% and that of IgM was 2.6%. Most of the study participants, 274 (79.4%) were family replacement donors. The majority of the blood donors 195 (56.5%) were anaemic (PCV < 36, Hb < 12g/dl). Those with positive CMV were more likely to be of high-income level (OR = 0.32, P = 0.04). Conclusion: the seroprevalence of CMV was high with a significant proportion of donors capable of transmitting CMV infection to blood recipients. The majority of the blood donors were anaemic. High income level is associated with CMV infection. Quality of screening for anemia be improved. Competing Interests: The authors declare no competing interests.
Databáze:	MEDLINE
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