Influenza B false-positive results by rapid molecular tests Alere™ i Influenza A&B 2 in France.

Autor: Otto MP; Service de microbiologie, Hôpital d'Instruction des Armées Sainte Anne, Toulon, France., Toyer AL; Service de biologie, C.H.I Toulon la Seyne sur mer, Toulon, France., Poggi C; Service de biologie, C.H.I Toulon la Seyne sur mer, Toulon, France., Janvier F; Service de microbiologie, Hôpital d'Instruction des Armées Sainte Anne, Toulon, France; Ecole du Val-de-Grâce, Paris, France. Electronic address: janvierfred@hotmail.com.
Jazyk: angličtina
Zdroj: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2019 Aug; Vol. 94 (4), pp. 342-343. Date of Electronic Publication: 2019 Mar 13.
DOI: 10.1016/j.diagmicrobio.2019.03.002
Abstrakt: The Alere-i™ Influenza A&B (Abbott), a nicking endonuclease amplification reaction test, has recently been improved in order to deliver results in a few minutes. Our field observation highlights two problems with this new version: improper interpretation of a test as valid despite improper reagent hydration and falsely influenza B positive results. We advise users of the new system to check reagent hydration prior to reporting a result and to systematically confirm positive influenza B results.
(Copyright © 2019 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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