Advanced glycation end products as biomarkers in systemic diseases: premises and perspectives of salivary advanced glycation end products.

Autor:	Băbţan AM; Department of Oral Rehabilitation, Oral Health & Dental Office Management, Faculty of Dentistry, 'Iuliu Haţieganu' University of Medicine & Pharmacy Cluj-Napoca, Romania, Victor Babe? Street, no 15, 400012, Romania., Ilea A; Department of Oral Rehabilitation, Oral Health & Dental Office Management, Faculty of Dentistry, 'Iuliu Haţieganu' University of Medicine & Pharmacy Cluj-Napoca, Romania, Victor Babe? Street, no 15, 400012, Romania., Boşca BA; Department of Histology, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine & Pharmacy Cluj-Napoca, Romania, Louis Pasteur Street, no 4, Cluj-Napoca, 400349, Romania., Crişan M; Department of Histology, Faculty of Medicine, 'Iuliu Haţieganu' University of Medicine & Pharmacy Cluj-Napoca, Romania, Louis Pasteur Street, no 4, Cluj-Napoca, 400349, Romania., Petrescu NB; Department of Oral Rehabilitation, Oral Health & Dental Office Management, Faculty of Dentistry, 'Iuliu Haţieganu' University of Medicine & Pharmacy Cluj-Napoca, Romania, Victor Babe? Street, no 15, 400012, Romania., Collino M; Department of Drug Science & Technology, University of Turin, Corso Raffaello 33, 10125 Torino, Italy., Sainz RM; Department of Morphology & Cell Biology, University of Oviedo, Campus del Cristo. C/Julián Clavería 6. 33006 Oviedo, Spain., Gerlach JQ; Glycoscience Group, National Centre for Biomedical Engineering Science, National University of Ireland Galway, H91 CF50 Galway, Ireland., Câmpian RS; Department of Oral Rehabilitation, Oral Health & Dental Office Management, Faculty of Dentistry, 'Iuliu Haţieganu' University of Medicine & Pharmacy Cluj-Napoca, Romania, Victor Babe? Street, no 15, 400012, Romania.
Jazyk:	angličtina
Zdroj:	Biomarkers in medicine [Biomark Med] 2019 Apr; Vol. 13 (6), pp. 479-495. Date of Electronic Publication: 2019 Apr 10.
DOI:	10.2217/bmm-2018-0448
Abstrakt:	Advanced glycation end products (AGEs) are glycated proteins associated with high dry temperature food processing, coloring and flavor modification of food products. Previous studies on diet-related disease support the role of the glycation products as biomarkers in local and general proinflammatory response. Exogenous and endogenous AGEs are involved in chronic low-level inflammation, which underlies the onset of metabolic syndrome influenced by food intake, there by demonstrating their implication in diet-related pathologies. Although studies have revealed a strong association between the accumulation of AGEs and the occurrence/worsening of metabolic diseases, their routine use for the diagnosis or monitoring of local and general disease has not yet been reported.
Databáze:	MEDLINE
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