Casein-derived peptides as an alternative ingredient for low-phenylalanine diets.

Autor: Krüger CCH; Food And Nutrition Post Graduate Program Federal University of Paraná., Azevedo TD; Food and Nutrition Post Graduate Program. Federal University of Paraná., Piltz MT; Food and Nutrition Post Graduate Program. Federal University of Paraná., Silva ÁT; Food and Nutrition Post Graduate Program. Federal University of Paraná., Cândido LMB; Food and Nutrition Post Graduate Program. Federal University of Paraná.
Jazyk: angličtina
Zdroj: Nutricion hospitalaria [Nutr Hosp] 2019 Jul 01; Vol. 36 (3), pp. 718-722.
DOI: 10.20960/nh.2391
Abstrakt: Introduction: Introduction: casein-derived peptides can be liberated both in vivo via normal digestion of casein, as well as in vitro via enzymatic hydrolysis. These peptides were suggested to have biological activity. Objectives: the aim of this study was to describe the production and characterization of casein peptides and to explore the potential of these peptides as an option for low-phenylalanine diets. Methods: peptides were produced by tryptic hydrolysis of sodium caseinate and acid precipitation with HCl, followed by precipitation with ethanol or aggregation of CaCl2 or ZnSO4. Results: the amino acid analysis revealed a significant reduction in the amount of phenylalanine from the original protein. Conclusion: casein-derived peptides could be a future alternative of short chain peptides to low-phenylalanine formulations.
Databáze: MEDLINE