Strongyloides stercoralis larvae in the urine of a patient with transitional cell carcinoma of the bladder: a case report.

Autor: Ita OI; 1Department of Medical Microbiology and Parasitology, University of Calabar, Calabar, Cross River State Nigeria., Akpayak IC; 2Division of Urology, Surgery Department, Jos University Teaching Hospital, Jos, Plateau State, Nigeria., Onyedibe KI; 3Department of Medical Microbiology, University of Jos, Jos, Plateau State, Nigeria., Otu AA; 4Department of Internal Medicine, University of Calabar, Calabar, Cross River State Nigeria.; 5Wythenshawe Hospital, Manchester University Foundation NHS Trust, Manchester, UK.
Jazyk: angličtina
Zdroj: Journal of parasitic diseases : official organ of the Indian Society for Parasitology [J Parasit Dis] 2019 Mar; Vol. 43 (1), pp. 154-157. Date of Electronic Publication: 2018 Nov 10.
DOI: 10.1007/s12639-018-1051-6
Abstrakt: Disseminated infection with Strongyloides stercoralis refers to the massive migration of infective larvae from the gastrointestinal tract to other organs that are not involved in the normal life cycle of the parasite. We describe the case of a Nigerian male with transitional cell carcinoma of the bladder in whom larvae of S. stercoralis was identified in the urine. This report involves a 60-year old male Nigerian presenting to the Urology clinic of the Jos University teaching hospital, Nigeria with disseminated S. stercoralis. The index patient presented with a 5 month history of total haematuria, urinary frequency, urgency, nocturia, straining to pass urine, feeling of incomplete voiding and terminal dribbling. He also had episodes of suprapubic pain. Physical examination revealed a cachexic patient who had mild suprapubic tenderness. Urinary examination showed numerous red blood cells and rhabditiform larvae of S. stercoralis . Abdominal ultrasound revealed a heterogeneous mass in the urinary bladder measuring 4.0 × 3.3 cm. Abdominal computed tomography also showed an irregular mass measuring 4.2 × 3.8 cm with HU of 41 projecting into the bladder from the posterior wall towards the dome. Histology of the biopsy specimen revealed transitional cell carcinoma. The patient was treated with a single dose of oral ivermectin but died 1 week later. Physicians working in areas that are endemic for S. stercoralis should consider investigating immunocompromised patients for S. stercoralis infection given the poor prognosis of disseminated infection in this group of patients.
Competing Interests: The authors declare that they have no conflict of interest.Informed consent was obtained from the next of kin of this patient to proceed with this report.
Databáze: MEDLINE
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