| Autor: |
Spear LP, Penson J, Linville DG |
| Jazyk: |
angličtina |
| Zdroj: |
Psychopharmacology [Psychopharmacology (Berl)] 1986; Vol. 90 (1), pp. 106-11. |
| DOI: |
10.1007/BF00172880 |
| Abstrakt: |
The effects of the GABA agonist muscimol and GABA antagonist picrotoxin were examined in 3-4-day-old deprived rat pups under conditions of low (absence of milk) and high (milk presence) activity baselines. A low dose of muscimol was observed to have activating effects under low baseline conditions, whereas higher doses of muscimol were observed to depress milk-induced activity and mouthing. Picrotoxin treatment was observed to increase activation of these neonates under both baseline conditions. Taken together, these results provide evidence for a functional GABAergic inhibition of behavior in the neonate. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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