| Autor: |
Sander MA; 1 Section of Dermatology, Department of Medicine, University of Calgary, AB, Canada., Sander MS; 2 Springbank Hill Dental, Calgary, AB, Canada., Isaac-Renton JL; 3 Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada., Croxen MA; 4 Provincial Laboratory for Public Health (ProvLab), Alberta Public Laboratories, Edmonton, AB, Canada.; 5 Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada. |
| Abstrakt: |
The human integument is inhabited by a vast array of microorganisms known collectively as the cutaneous microbiome. As a result of advances in laboratory science, our understanding of the diversity and complexity of the human microbiome is rapidly evolving. In particular, advances in the field of genomics have enabled the study of the cutaneous microbiome with a hitherto unimaginable level of detail, resulting in a maturation of our understanding of cutaneous health and disease. Herein, we review current microbiology concepts and highlight the key features of recent laboratory advances, particularly with respect to genomics. We provide a summary of new findings related to normal skin flora, interactions between host immunity and microbial communities, and microbial relationships with common skin disorders. Finally, we review the implications for dermatologists. |
