Findings in Appendectomies with Enterobius vermicularis Infection: Pinworm Is Not A Cause of Appendicitis

Autor:	Pehlivanoğlu B; Adıyaman University Training and Research Hospital, Department of Pathology, Adıyaman, Turkey, Aydın Türk B; Adıyaman University Training and Research Hospital, Department of Pathology, Adıyaman, Turkey, İşler S; Adıyaman University Training and Research Hospital, Department of Pathology, Adıyaman, Turkey, Özdaş S; Adıyaman University Training and Research Hospital, Department of General Surgery, Adıyaman, Turkey, Abeş M; Adıyaman University Faculty of Medicine, Department of Pediatric Surgery, Adıyaman, Turkey
Jazyk:	angličtina
Zdroj:	Turkiye parazitolojii dergisi [Turkiye Parazitol Derg] 2019 Mar 28; Vol. 43 (1), pp. 21-25.
DOI:	10.4274/tpd.galenos.2019.6177
Abstrakt:	Objective: To evaluate the histopathological findings in appendectomy materials with E. vermicularis infection. Methods: Appendectomy materials with E. vermicularis infection of 24 cases were evaluated for the presence of acute inflammation, congestion, hemorrhage, perforation, lymphoid hyperplasia (LH), necrosis, granuloma, fecalith, obliteration, hyalinization, eosinophilic infiltration and mucosal architectural distortion. Results: The frequency of E. vermicularis among 3222 appendectomies that were scanned for the study was 0.74% (24/3222). Female: male ratio was 1:1 and the median age was 12±9.34 years. The most common findings were LH (100%), and congestion (91.7%) Acute inflammation was found in one third (n=8), with phlegmonous inflammation and/or periappendicitis in 4 of them. The patients with periappendicitis were significantly younger (mean age 4 vs. 14.2 years, p=0.008). Feces was present in the lumen in 79.1% of the patients (fecalith in 25%, soft feces in 29.1% and feces mixed with blood and/or suppuration in 25%). In 6 cases (25%), only E. vermicularis was observed in the lumen, with acute appendicitis in 2 of them. Appendiceal lumen was completely obstructed in 12.5% (n=3), while it seemed narrow due to extensive LH in 3 (12.5%) cases. Fibrous obliteration was seen in 4 patients and it was correlated with age and eosinophil count in lamina propria p<0.05. Conclusion: While E. vermicularis infection appears to be an incidental finding in appendectomies rather than being a cause of appendicitis, it probably stimulates LH which may mimic acute appendicitis clinically.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu