Secondary Metabolites of Endophytic Actinomycetes: Isolation, Synthesis, Biosynthesis, and Biological Activities.

Autor:	Bernardi DI; Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., das Chagas FO; Instituto de Pesquisa de Produtos Naturais Walter Mors, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Monteiro AF; Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., Dos Santos GF; Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., de Souza Berlinck RG; Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil. rgsberlinck@iqsc.usp.br.
Jazyk:	angličtina
Zdroj:	Progress in the chemistry of organic natural products [Prog Chem Org Nat Prod] 2019; Vol. 108, pp. 207-296.
DOI:	10.1007/978-3-030-01099-7_3
Abstrakt:	Endophytic Actinobacteria are a microbial group that is still poorly investigated. Their association with plants constitutes a unique trait conferring specific biological and chemical features to endophytic Actinobacteria. This contribution discusses aspects of endophytic actinobacterial biology and chemistry comprehensively, including the biosynthesis and total synthesis of secondary metabolites produced in culture. It also presents perspectives for the future of microbial bioactive natural products discovery, with emphasis on the secondary metabolism of endophytic Actinobacteria.
Databáze:	MEDLINE
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