Discovery of Cucumis melo endornavirus by deep sequencing of human stool samples in Brazil.

Autor: da Costa AC; Institute of Tropical Medicine, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, no 470, São Paulo, São Paulo, 05403-000, Brazil. charlysbr@yahoo.com.br.; LIM/46, Faculty of Medicine, University of São Paulo, São Paulo, Brazil. charlysbr@yahoo.com.br., Leal E; Institute of Biological Sciences, Federal University of Pará, Belém do Pará, Brazil., Gill D; Institute of Tropical Medicine, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, no 470, São Paulo, São Paulo, 05403-000, Brazil.; LIM/46, Faculty of Medicine, University of São Paulo, São Paulo, Brazil., Milagres FAP; Federal University of Tocantins, Palmas, Brazil.; Public Health Laboratory of Tocantins State (LACEN/TO), Palmas, Brazil.; Secretary of Health of Tocantins, Palmas, Brazil., Komninakis SV; Postgraduate Program in Health Science, Faculty of Medicine of ABC, Santo André, Brazil.; Retrovirology Laboratory, Federal University of São Paulo, São Paulo, São Paulo, Brazil., Brustulin R; Federal University of Tocantins, Palmas, Brazil.; Public Health Laboratory of Tocantins State (LACEN/TO), Palmas, Brazil.; Secretary of Health of Tocantins, Palmas, Brazil., Teles MDAR; Public Health Laboratory of Tocantins State (LACEN/TO), Palmas, Brazil.; Secretary of Health of Tocantins, Palmas, Brazil., Lobato MCABS; Public Health Laboratory of Tocantins State (LACEN/TO), Palmas, Brazil.; Secretary of Health of Tocantins, Palmas, Brazil., das Chagas RT; Public Health Laboratory of Tocantins State (LACEN/TO), Palmas, Brazil.; Secretary of Health of Tocantins, Palmas, Brazil., Abrão MFNDS; Public Health Laboratory of Tocantins State (LACEN/TO), Palmas, Brazil.; Secretary of Health of Tocantins, Palmas, Brazil., Soares CVDA; Public Health Laboratory of Tocantins State (LACEN/TO), Palmas, Brazil.; Secretary of Health of Tocantins, Palmas, Brazil., Deng X; Blood Systems Research Institute, San Francisco, USA.; Department Laboratory Medicine, University of California San Francisco, San Francisco, USA., Delwart E; Blood Systems Research Institute, San Francisco, USA.; Department Laboratory Medicine, University of California San Francisco, San Francisco, USA., Sabino EC; Institute of Tropical Medicine, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, no 470, São Paulo, São Paulo, 05403-000, Brazil.; LIM/46, Faculty of Medicine, University of São Paulo, São Paulo, Brazil., Luchs A; Enteric Disease Laboratory, Virology Center, Adolfo Lutz Institute, Av. Dr Arnaldo, no 355, São Paulo, São Paulo, 01246-902, Brazil. driluchs@gmail.com.
Jazyk: angličtina
Zdroj: Virus genes [Virus Genes] 2019 Jun; Vol. 55 (3), pp. 332-338. Date of Electronic Publication: 2019 Mar 26.
DOI: 10.1007/s11262-019-01648-0
Abstrakt: The nearly complete genome sequences of two Cucumis melo endornavirus (CmEV) strains were obtained using deep sequencing while investigating fecal samples for the presence of gastroenteritis viruses. The Brazilian CmEV BRA/TO-23 (aa positions 116-5027) and BRA/TO-74 (aa positions 26-5057) strains were nearly identical to the reference CmEV CL-01 (USA) and SJ1 (South Korea) strains, showing 97% and 98% of nucleotide and amino acid identity, respectively. Endornaviruses are not known to be associated with human disease and their presence may simply reflect recent dietary consumption. Metagenomic analyses offered an opportunity to identify for the first time in Brazil a newly described endornavirus species.
Databáze: MEDLINE
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