Indicator PCBs in farmed and wild fish in Greece - Risk assessment for the Greek population.

Autor: Renieri EA; Centre of Toxicology Science and Research, University of Crete, School of Medicine, Crete, Greece. Electronic address: e.renieri@med.uoc.gr., Goumenou M; Centre of Toxicology Science and Research, University of Crete, School of Medicine, Crete, Greece., Kardonsky DA; Center of Bioanalytical Research and Molecular Design, FSAEI HE I.M. Sechenov First MSMU MOH Russia, Sechenov University, Russia., Veselov VV; Center of Bioanalytical Research and Molecular Design, FSAEI HE I.M. Sechenov First MSMU MOH Russia, Sechenov University, Russia., Alegakis AΚ; Centre of Toxicology Science and Research, University of Crete, School of Medicine, Crete, Greece., Buha A; Department of Toxicology 'Akademik Danilo Soldatovic', University of Belgrade-Faculty of Pharmacy, Belgrade, Serbia., Tzatzarakis MN; Centre of Toxicology Science and Research, University of Crete, School of Medicine, Crete, Greece., Nosyrev AE; Center of Bioanalytical Research and Molecular Design, FSAEI HE I.M. Sechenov First MSMU MOH Russia, Sechenov University, Russia., Rakitskii VN; FBES, FSCH Named after F.F. Erisman» of the Rospotrebnadzor, Mytishchi, Russia., Kentouri M; Biology Department, University of Crete, Heraklion, Crete, Greece., Tsatsakis A; Centre of Toxicology Science and Research, University of Crete, School of Medicine, Crete, Greece.
Jazyk: angličtina
Zdroj: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2019 May; Vol. 127, pp. 260-269. Date of Electronic Publication: 2019 Mar 18.
DOI: 10.1016/j.fct.2019.03.027
Abstrakt: Health benefits of fish consumption could be counterbalanced by the intake of contaminants after long term fish consumption, burdened even in trace levels. The presence of the indicator PCBs (NDL-PCBs and PCB 118) in farmed and wild seabream and seabass was evaluated. For the determination of PCB, a GC-MS method was developed and evaluated. The association of PCB accumulation in fish with seasonality, locality, production mode and species was also investigated. A new approach for the risk characterisation after exposure to NDL-PCB through fish consumption in Greece was developed, based on the real exposure and the permitted maximum levels of both aggregated dietary exposure and exposure through fish consumption. PCB levels determined in fish were below established permitted limits (6.24 ng/g 95th percentile), while PCB levels and congener distribution varied significantly between farmed and wild fish (p = 0.001). Seasonality was highlighted as an important factor affecting NDL-PCBs accumulation, with high levels coinciding with the reproduction period of each species. Differences were also depicted for sampling sites, with PCB 118 presenting significantly higher values in open seas while NDL-PCB congeners in closed seas. Risk assessment of NDL-PCB intake through fish consumption corrected for the aggregated exposure revealed no risk for the consumers.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: