Pancreatic cancer: Best supportive care.

Autor: Védie AL; Assistance publique-Hopitaux de Paris (AP-HP), Beaujon University Hospital, Department of Gastroenterology and Pancreatology, Paris 7 Diderot University, 100, boulevard du Général-Leclerc, 92110 Clichy, France., Neuzillet C; Paris 7 Diderot University, Centre de recherche sur l'inflammation, Inserm UMR1149, 100, boulevard du Général-Leclerc, 92110 Clichy La Garenne, France; Curie Institute, Medical Oncology Department, Versailles Saint Quentin University, 35, rue Dailly, 92210 Saint-Cloud, France. Electronic address: cindy.neuzillet@gmail.com.
Jazyk: angličtina
Zdroj: Presse medicale (Paris, France : 1983) [Presse Med] 2019 Mar; Vol. 48 (3 Pt 2), pp. e175-e185. Date of Electronic Publication: 2019 Mar 14.
DOI: 10.1016/j.lpm.2019.02.032
Abstrakt: Palliative and supportive care holds a major place in pancreatic ductal adenocarcinoma (PDAC) management. It aims to prevent and reduce symptoms and hospital admissions, while ensuring optimal health-related quality of life (HRQoL), which has been reported to be correlated with overall survival in PDAC. Best supportive care includes non-specific treatment of pain, anxiety and depression, chemotherapy-related toxicities, as well as thromboembolic disease treatment and prevention in high-risk patients. Moreover, nutrition and physical activity interventions are receiving increasing attention as they are crucial to optimize treatment tolerance and efficacy. Of note, they require adaptation to the specificities of PDAC setting and stage of the disease. In this review, we propose an overview of palliative and supportive care interventions in PDAC, with a highlight on nutritional and physical activity management.
(Copyright © 2019 Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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