Oocyte cryopreservation for future fertility: comparison of ovarian response between cancer and non-cancer patients.

Autor:	Moraes CC; Pró-Criar Medicina Reprodutiva, Belo Horizonte, MG, Brazil.; Faculdade Ciências Médicas Minas Gerais, Belo Horizonte, MG, Brazil., Marinho VFW; Faculdade Ciências Médicas Minas Gerais, Belo Horizonte, MG, Brazil., Campos ALM; Pró-Criar Medicina Reprodutiva, Belo Horizonte, MG, Brazil.; Faculdade Ciências Médicas Minas Gerais, Belo Horizonte, MG, Brazil., Guedes JS; Faculdade Ciências Médicas Minas Gerais, Belo Horizonte, MG, Brazil., Xavier ÉBS; Pró-Criar Medicina Reprodutiva, Belo Horizonte, MG, Brazil.; Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Caetano JPJ; Pró-Criar Medicina Reprodutiva, Belo Horizonte, MG, Brazil., Marinho RM; Pró-Criar Medicina Reprodutiva, Belo Horizonte, MG, Brazil.; Faculdade Ciências Médicas Minas Gerais, Belo Horizonte, MG, Brazil.
Jazyk:	angličtina
Zdroj:	JBRA assisted reproduction [JBRA Assist Reprod] 2019 Apr 30; Vol. 23 (2), pp. 91-98. Date of Electronic Publication: 2019 Apr 30.
DOI:	10.5935/1518-0557.20190010
Abstrakt:	Objective: This study aimed to assess whether a diagnosis of cancer interferes with ovarian function prior to the treatment of the disease. Methods: This observational retrospective study used data from medical records of ovarian stimulation cycles performed for purposes of oocyte cryopreservation. Results: The included patients had a mean age of 35.13±3.72 years and 51.6% of them were aged between 36 and 40 years. More than half of the patients (57.6%) were single and 82.1% had a normal body mass index (BMI). Most women had not become pregnant (85.5%) or had babies (95.1%) or miscarriages (89.6%) prior to cryopreservation. The mean number of oocytes obtained from non-cancer patients was 11.4±8, while for cancer patients the number was 13.8±9. The mean number of frozen mature oocytes was 9.7±7 for the non-cancer group and 11.2±7.2 for the cancer group. The majority (63.1%) of the patients had up to 10 oocytes frozen per cycle. Breast cancer had the highest incidence among the included patients. There was no significant difference in ovarian response between patients with different types of cancer. Conclusion: The number of harvested and frozen oocytes from cancer and non-cancer patients indicated that in the two groups response to ovarian stimulation was similar.
Databáze:	MEDLINE
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