Epidemiological features and risk factors for mortality in Pseudomonas aeruginosa bacteremia in children.

Autor: Rosanova MT; Servicio de Control Epidemiológico e Infectología. Hospital de Pediatría SAMIC 'Prof. Dr. Juan P. Garrahan', Ciudad Autónoma de Buenos Aires., Mussini MS; Servicio de Control Epidemiológico e Infectología. Hospital de Pediatría SAMIC 'Prof. Dr. Juan P. Garrahan', Ciudad Autónoma de Buenos Aires., Arias AP; Servicio de Control Epidemiológico e Infectología. Hospital de Pediatría SAMIC 'Prof. Dr. Juan P. Garrahan', Ciudad Autónoma de Buenos Aires. margris2@yahoo.com.ar., Sormani MI; Servicio de Control Epidemiológico e Infectología. Hospital de Pediatría SAMIC 'Prof. Dr. Juan P. Garrahan', Ciudad Autónoma de Buenos Aires., Mastroianni A; Servicio de Microbiología. Hospital de Pediatría SAMIC 'Prof. Dr. Juan P. Garrahan', Ciudad Autónoma de Buenos Aires., García ME; Servicio de Microbiología. Hospital de Pediatría SAMIC 'Prof. Dr. Juan P. Garrahan', Ciudad Autónoma de Buenos Aires., Reijtman V; Servicio de Microbiología. Hospital de Pediatría SAMIC 'Prof. Dr. Juan P. Garrahan', Ciudad Autónoma de Buenos Aires., Sarkis C; Servicio de Control Epidemiológico e Infectología. Hospital de Pediatría SAMIC 'Prof. Dr. Juan P. Garrahan', Ciudad Autónoma de Buenos Aires.
Jazyk: English; Spanish; Castilian
Zdroj: Archivos argentinos de pediatria [Arch Argent Pediatr] 2019 Apr 01; Vol. 117 (2), pp. 128-131.
DOI: 10.5546/aap.2019.eng.128
Abstrakt: The objective was to describe the epidemiological, clinical, microbiological, and evolutionary characteristics and the risk factors for mortality. Retrospective, cohort study. A total of 100 patients were included. Of these, 42 (42 %) had septic shock upon admission and 56 (56 %) were admitted to the intensive care unit. Bacteremia was primary in 17 patients (17 %); catheter-related, in 15 (15 %); and secondary, in 68 (68 %). The most common source of infection was the skin and mucous membrane. Resistance to one or more antibiotic groups was 38 %. Thirty-one patients died (31 %). Risk factors for mortality were septic shock (p < 0.0005), admission to the intensive care unit (p < 0.0001), primary bacteremia (p < 0.009) or secondary, non-catheter-related bacteremia (p < 0.003), presence of mucocutaneous or pulmonary source of infection (p < 0.004), and multidrug resistance (p < 0.01) or resistance to carbapenems (p < 0.01).
(Sociedad Argentina de Investigación Odontológica.)
Databáze: MEDLINE