High genetic diversity of noroviruses in children from a community-based study in Rio de Janeiro, Brazil, 2014-2018.

Autor: Cantelli CP; Technology Institute for Immunobiologicals/Bio-Manguinhos, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro, Brazil. carina.cantelli@gmail.com.; Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, 4365, Pav. Hélio & Peggy Pereira, Manguinhos, Rio de Janeiro, 21040-360, Brazil. carina.cantelli@gmail.com., da Silva MFM; Tropical Pathology and Public Health Institute, Federal University of Goiás, Rua 235, Goiânia, Brazil., Fumian TM; Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, 4365, Pav. Hélio & Peggy Pereira, Manguinhos, Rio de Janeiro, 21040-360, Brazil., da Cunha DC; Sérgio Arouca, Public Health National School, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro, Brazil., Andrade JDSR; Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, 4365, Pav. Hélio & Peggy Pereira, Manguinhos, Rio de Janeiro, 21040-360, Brazil., Malta FC; Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, 4365, Pav. Hélio & Peggy Pereira, Manguinhos, Rio de Janeiro, 21040-360, Brazil., da Silva E Mouta Junior S; Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, 4365, Pav. Hélio & Peggy Pereira, Manguinhos, Rio de Janeiro, 21040-360, Brazil., Fialho AM; Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, 4365, Pav. Hélio & Peggy Pereira, Manguinhos, Rio de Janeiro, 21040-360, Brazil., de Moraes MTB; Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, 4365, Pav. Hélio & Peggy Pereira, Manguinhos, Rio de Janeiro, 21040-360, Brazil., Brasil P; Evandro Chagas National Institute of Infectious Diseases, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro, Brazil., Miagostovich MP; Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, 4365, Pav. Hélio & Peggy Pereira, Manguinhos, Rio de Janeiro, 21040-360, Brazil., Leite JPG; Laboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, 4365, Pav. Hélio & Peggy Pereira, Manguinhos, Rio de Janeiro, 21040-360, Brazil.
Jazyk: angličtina
Zdroj: Archives of virology [Arch Virol] 2019 May; Vol. 164 (5), pp. 1427-1432.
DOI: 10.1007/s00705-019-04195-z
Abstrakt: We report on the occurrence and diversity of noroviruses in children (younger than 5 years old of age) from a low-income urban area in Rio de Janeiro, Brazil. Sixty-one stool specimens collected from children between 1 and 4 years old with acute diarrhoeic episodes (ADE) and non-ADE were investigated. RT-qPCR and sequencing of PCR products after conventional RT-PCR analysis were performed. Noroviruses were detected in 29 (47.5%) samples: 21 (46.7%) from cases with ADE and 8 (50%) from non-ADE cases. Molecular characterization showed 10 different genotypes circulating in this community between November 2014 and April 2018.
Databáze: MEDLINE
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