Enhancing adhesion and alignment of human gingival fibroblasts on dental implants.

Autor: Aktas OC; Institute for Materials Science, Christian-Albrechts-University Kiel, Germany., Metzger W; Department of Trauma, Hand and Reconstructive Surgery, Saarland University, Homburg, Saar, Germany., Haidar A; Department of Prosthetic Dentistry and Dental Materials Sciences, Saarland University, Homburg, Saar, Germany., Açil Y; Department of Oral and Maxillofacial Surgery, Christian-Albrecht-Universität zu Kiel, Kiel, Germany., Gülses A; Department of Oral and Maxillofacial Surgery, Christian-Albrecht-Universität zu Kiel, Kiel, Germany., Wiltfang J; Department of Oral and Maxillofacial Surgery, Christian-Albrecht-Universität zu Kiel, Kiel, Germany., Sacramento CM; Department of Prosthesis and Periodontology, Division of Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil., Nothdurft FP; Department of Prosthetic Dentistry and Dental Materials Sciences, Saarland University, Homburg, Saar, Germany. Electronic address: frank.nothdurft@uks.eu.
Jazyk: angličtina
Zdroj: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery [J Craniomaxillofac Surg] 2019 Apr; Vol. 47 (4), pp. 661-667. Date of Electronic Publication: 2019 Feb 21.
DOI: 10.1016/j.jcms.2019.02.004
Abstrakt: Background: Promoting the directional attachment of gingiva to the dental implant leads to the formation of tight connective tissue which acts as a seal against the penetration of oral bacteria. Such a directional growth is mostly governed by the surface texture.
Material and Methods: In this study, three different methods, mechanical structuring, chemical etching and laser treatment, have been explored for their applicability in promoting cellular attachment and alignment of human primary gingival fibroblasts (HGFIBs).
Results: The effectiveness of mechanical structuring was shown as a simple and a cost-effective method to create patterns to align HGIFIBs.
Conclusion: Combining mechanical structuring with chemical etching enhanced both cellular attachment and the cellular alignment.
(Copyright © 2019 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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