SuFEx-based strategies for the preparation of functional particles and cation exchange resins.

Autor: Kassick AJ; Neuroscience Disruptive Research Lab, Allegheny Health Network Research Institute, Allegheny General Hospital, Pittsburgh, PA 15212, USA. saadyah.averick@ahn.org and Neuroscience Institute, Allegheny Health Network, Allegheny General Hospital, Pittsburgh, PA 15212, USA., Chen L; Department of Chemistry and College of Engineering, University of Georgia, Athens, GA 30602, USA., Kovaliov M; Neuroscience Disruptive Research Lab, Allegheny Health Network Research Institute, Allegheny General Hospital, Pittsburgh, PA 15212, USA. saadyah.averick@ahn.org and Neuroscience Institute, Allegheny Health Network, Allegheny General Hospital, Pittsburgh, PA 15212, USA., Mathers RT; Department of Chemistry, The Pennsylvania State University, New Kensington, PA 15068, USA., Locklin J; Department of Chemistry and College of Engineering, University of Georgia, Athens, GA 30602, USA., Averick S; Neuroscience Disruptive Research Lab, Allegheny Health Network Research Institute, Allegheny General Hospital, Pittsburgh, PA 15212, USA. saadyah.averick@ahn.org and Neuroscience Institute, Allegheny Health Network, Allegheny General Hospital, Pittsburgh, PA 15212, USA.
Jazyk: angličtina
Zdroj: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2019 Apr 07; Vol. 55 (27), pp. 3891-3894. Date of Electronic Publication: 2019 Mar 07.
DOI: 10.1039/c9cc00036d
Abstrakt: A predictable and reproducible number of sulfuric acid sites have been achieved for cation exchange resins by employing a mild SuFEx-based reagent system to effect the hydrolysis of fluorosulfonated polymer beads. The resultant poly(hydrogen sulfate) beads effectively demonstrate their utility as cation exchange resins in ion-capture experiments. Furthermore, their polyfluorosulfonated precursors have also proven to be suitable substrates for traditional SuFEx-type click reactions in both small molecule and protein immobilization applications.
Databáze: MEDLINE