Mid-term outcome of severe tricuspid regurgitation: are there any differences according to mechanism and severity?

Autor:	Santoro C; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Marco Del Castillo A; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., González-Gómez A; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Monteagudo JM; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Hinojar R; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Lorente A; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Abellás M; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Vieitez JM; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Garcia Martìn A; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Casas Rojo E; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Ruíz S; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Barrios V; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Luis Moya J; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Jimenez-Nacher JJ; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Zamorano Gomez JL; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain., Fernández-Golfín C; Cardiac Imaging Unit, Cardiology Department, Ramón y Cajal University Hospital, Carretera de Colmenar Km 9, 100, Madrid 28034, Madrid, Spain.; CIBERCV, Instituto de Salud Carlos III (ISCIII), Spain.
Jazyk:	angličtina
Zdroj:	European heart journal. Cardiovascular Imaging [Eur Heart J Cardiovasc Imaging] 2019 Sep 01; Vol. 20 (9), pp. 1035-1042.
DOI:	10.1093/ehjci/jez024
Abstrakt:	Aims: Patients with significant tricuspid regurgitation (TR) addressed according the new classification in torrential TR may have different prognosis compared with just severe TR patients. We sought to determine distribution and mechanism of consecutive severe TR patients, in accordance with aetiology and severity by applying the new proposed classification scheme and their long-term outcomes. Methods and Results: Between January and December 2013, 249 patients with significant TR referred to the cardiac imaging unit (mean age 79.9 ± 10.2 years; 29.8% female) were included. Patients were divided according to aetiology in six groups, and TR severity was reclassified into severe, massive, and torrential TR. The follow-up period was of 313 ± 103 days. When considering cardiovascular mortality, patients in the massive/torrential group showed the highest number of events (P < 0.007). Patients with TR due to pulmonary diseases had the worst prognosis according to different aetiology. Noteworthy, the best predictors for the combined endpoint [cardiovascular mortality and readmission admission for heart failure (HF)] were TR severity according to the new classification [hazard ratio (HR) 2.48, 95% confidence interval (CI) 1.25-4.93] and clinical scores such as New York Heart Association classification and congestive status (HR 1.78, 95% CI 1.28-2.49; HR 2.08, 95% CI 1.06-4.06, respectively). Conclusion: Patients with massive/torrential TR and patients with comorbidities, especially pulmonary disease, were identified as populations at higher risk of death and readmission for HF. New classification scheme and clinical assessment may establish who may benefit the most of intensive therapeutic treatments and intervention on the tricuspid valve. (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.)
Databáze:	MEDLINE
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